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Nucleic Acids

Known as: Nucleic Acid, Nucleic Acids [Chemical/Ingredient], acids nucleic 
High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.
National Institutes of Health

Related topics

Related topics

33 relations

Broader (4)

AcidsNucleic Acids, Nucleotides, and NucleosidesPolynucleotidesnatural polymers

Narrower (15)

AdenosineAntisense Elements (Genetics)DNADNA, B-Form
Core AssemblyGenetics, BiochemicalGuanosineIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Cell-free nucleic acids as biomarkers in cancer patients
DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic… 
Highly Cited
2010
Highly Cited
2010
MolProbity: all-atom structure validation for macromolecular crystallography
MolProbity structure validation will diagnose most local errors in macromolecular crystal structures and help to guide their… 
Highly Cited
2007
Highly Cited
2007
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes… 
Highly Cited
2003
Highly Cited
2003
Mfold web server for nucleic acid folding and hybridization prediction
  • M. Zuker
  • Nucleic Acids Res.
  • 2003
  • Corpus ID: 13494853
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide… 
Highly Cited
2001
Highly Cited
2001
A new mathematical model for relative quantification in real-time RT-PCR.
  • M. Pfaffl
  • Nucleic acids research
  • 2001
  • Corpus ID: 9003591
Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to… 
Highly Cited
1996
Highly Cited
1996
VMD: visual molecular dynamics.
Highly Cited
1990
Highly Cited
1990
Rapid and simple method for purification of nucleic acids
We have developed a simple, rapid, and reliable protocol for the small-scale purification of DNA and RNA from, e.g., human serum… 
Highly Cited
1974
Highly Cited
1974
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
A structure for nucleic acid has already been proposed by Pauling and Corey [1]. They kindly made'their manuscript available to… 
Highly Cited
1974
Highly Cited
1974
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.
A simple method is described for detecting 3H in polyacrylamide gels by scintillation autography (fluorography) using X-ray film… 
Highly Cited
1953
Highly Cited
1953
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
The determination in 1953 of the structure of deoxyribonucleic acid (DNA), with its two entwined helices and paired organic bases… 
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