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Nucleic Acids
Known as:
Nucleic Acid
, Nucleic Acids [Chemical/Ingredient]
, acids nucleic
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High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.
National Institutes of Health
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Related topics
Related topics
33 relations
Broader (4)
Acids
Nucleic Acids, Nucleotides, and Nucleosides
Polynucleotides
natural polymers
Narrower (15)
Adenosine
Antisense Elements (Genetics)
DNA
DNA, B-Form
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Core Assembly
Genetics, Biochemical
Guanosine
In Blood
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Cell-free nucleic acids as biomarkers in cancer patients
H. Schwarzenbach
,
D. Hoon
,
K. Pantel
Nature Reviews Cancer
2011
Corpus ID: 6061607
DNA, mRNA and microRNA are released and circulate in the blood of cancer patients. Changes in the levels of circulating nucleic…
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Highly Cited
2010
Highly Cited
2010
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen
,
W. B. Arendall
,
+6 authors
D. Richardson
Acta crystallographica. Section D, Biological…
2010
Corpus ID: 1028282
MolProbity structure validation will diagnose most local errors in macromolecular crystal structures and help to guide their…
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Highly Cited
2007
Highly Cited
2007
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
Ian W. Davis
,
A. Leaver-Fay
,
+8 authors
D. Richardson
Nucleic Acids Res.
2007
Corpus ID: 15207498
MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes…
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Highly Cited
2003
Highly Cited
2003
Mfold web server for nucleic acid folding and hybridization prediction
M. Zuker
Nucleic Acids Res.
2003
Corpus ID: 13494853
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide…
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Highly Cited
2001
Highly Cited
2001
A new mathematical model for relative quantification in real-time RT-PCR.
M. Pfaffl
Nucleic acids research
2001
Corpus ID: 9003591
Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to…
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Highly Cited
1996
Highly Cited
1996
VMD: visual molecular dynamics.
W. Humphrey
,
A. Dalke
,
K. Schulten
Journal of molecular graphics
1996
Corpus ID: 23780026
Highly Cited
1990
Highly Cited
1990
Rapid and simple method for purification of nucleic acids
R. Boom
,
C. Sol
,
M. Salimans
,
C. Jansen
,
P. W. Wertheim-van Dillen
,
J. van der Noordaa
Journal of clinical microbiology
1990
Corpus ID: 25732153
We have developed a simple, rapid, and reliable protocol for the small-scale purification of DNA and RNA from, e.g., human serum…
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Highly Cited
1974
Highly Cited
1974
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
J. Watson
,
F. Crick
Nature
1974
Corpus ID: 4191927
A structure for nucleic acid has already been proposed by Pauling and Corey [1]. They kindly made'their manuscript available to…
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Highly Cited
1974
Highly Cited
1974
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.
W. Bonner
,
R. Laskey
European journal of biochemistry
1974
Corpus ID: 27417779
A simple method is described for detecting 3H in polyacrylamide gels by scintillation autography (fluorography) using X-ray film…
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Highly Cited
1953
Highly Cited
1953
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
J. Watson
,
F. Crick
Nature
1953
Corpus ID: 4253007
The determination in 1953 of the structure of deoxyribonucleic acid (DNA), with its two entwined helices and paired organic bases…
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