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Core Assembly

Assembly of virus core.
National Institutes of Health

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2 relations
Lytic PhaseNucleic Acids

Papers overview

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2015
2015
Electron cryotomography studies of maturing HIV-1 particles reveal the assembly pathway of the viral core.
UNLABELLED To better characterize the assembly of the HIV-1 core, we have used electron cryotomography (ECT) to image infected… Expand
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2010
2010
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
BackgroundThe HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of… Expand
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2008
2008
VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability
BackgroundThe machinery of early HIV-1 replication still remains to be elucidated. Recently the viral core was reported to… Expand
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Highly Cited
2006
Highly Cited
2006
The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions.
Infectious HIV particles contain a characteristic cone-shaped core encasing the viral RNA and replication proteins. The core… Expand
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2004
2004
snRNAs contain specific SMN-binding domains that are essential for snRNP assembly.
To serve in its function as an assembly machine for spliceosomal small nuclear ribonucleoprotein particles (snRNPs), the survival… Expand
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Highly Cited
2001
Highly Cited
2001
Alphavirus nucleocapsid protein contains a putative coiled coil alpha-helix important for core assembly.
The alphavirus nucleocapsid core is formed through the energetic contributions of multiple noncovalent interactions mediated by… Expand
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Highly Cited
2000
Highly Cited
2000
Proline residues in the HIV-1 NH2-terminal capsid domain: structure determinants for proper core assembly and subsequent steps of early replication.
Recent analyses suggest that the p24 capsid (p24(CA)) domain of the HIV-1 group-specific antigen (Gag) may be divided into two… Expand
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Highly Cited
1999
Highly Cited
1999
Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26.
Two crystal forms of recombinant p26 capsid protein (CA) from the equine infectious anemia virus (EIAV) have in common an… Expand
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Highly Cited
1999
Highly Cited
1999
Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner.
The association of Sm proteins with U small nuclear RNA (snRNA) requires the single-stranded Sm site (PuAU(4-6)GPu) but also is… Expand
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Highly Cited
1998
Highly Cited
1998
Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly.
After budding, the human immunodeficiency virus (HIV) must 'mature' into an infectious viral particle. Viral maturation requires… Expand
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