Nuclear Transfer Techniques

Hyperacute rejection of porcine organs by old world primate recipients is mediated through preformed antibodies against… (More)

Active demethylation of cytosine residues in the sperm genome before forming a functional zygotic nucleus is thought to be an… (More)

The presence of galactose alpha-1,3-galactose residues on the surface of pig cells is a major obstacle to successful… (More)

Cloning from somatic cells is inefficient, with most clones dying during gestation. Cloning from embryonic stem (ES) cells is… (More)

Sheep, mice, cattle, goats and pigs have all been cloned by transfer of a donor cell nucleus into an enucleated ovum, and now we… (More)

It is over a decade since the first demonstration that mouse embryonic stem cells could be used to transfer a predetermined… (More)

Successful cryopreservation of mammalian oocytes would provide a steady source of materials for nuclear transfer and in vitro… (More)

In this study, we demonstrate the production of transgenic goats by nuclear transfer of fetal somatic cells. Donor karyoplasts… (More)

Nuclear transplantation and cell fusion techniques have proved valuable for embryological studies in several non-mammalian animal… (More)

In 1962 researcher John Bertrand Gurdon at the University of Oxford [3] in Oxford, England conducted a series of experiments on… (More)