A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
- J. Polo, E. Anderssen, K. Hochedlinger
- BiologyCell
- 21 December 2012
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
- Marius Wernig, A. Meissner, R. Jaenisch
- BiologyNature
- 19 July 2007
The results show that the biological potency and epigenetic state of in-vitro-reprogrammed induced pluripotent stem cells are indistinguishable from those of ES cells.
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.
- N. Maherali, R. Sridharan, K. Hochedlinger
- BiologyCell Stem Cell
- 7 June 2007
Disease-Specific Induced Pluripotent Stem Cells
- In-Hyun Park, Natasha Arora, G. Daley
- Biology, MedicineCell
- 5 September 2008
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.
- M. Stadtfeld, N. Maherali, D. Breault, K. Hochedlinger
- BiologyCell Stem Cell
- 6 March 2008
Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.
- Katrin Arnold, Abby Sarkar, K. Hochedlinger
- BiologyCell Stem Cell
- 4 October 2011
Efficient method to generate single‐copy transgenic mice by site‐specific integration in embryonic stem cells
- C. Beard, K. Hochedlinger, K. Plath, A. Wutz, R. Jaenisch
- BiologyGenesis
- 1 January 2006
A transgene integration strategy mediated by site‐specific recombination that allows establishment of multiple embryonic stem cell lines carrying tetracycline‐inducible genes targeted to a specific locus to assure predictable temporal and spatial expression in ES cells and mice is described.
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
- M. Stadtfeld, E. Apostolou, K. Hochedlinger
- BiologyNature
- 13 May 2010
Overall messenger RNA and microRNA expression patterns are indistinguishable with the exception of a few transcripts encoded within the imprinted Dlk1–Dio3 gene cluster on chromosome 12qF1, which were aberrantly silenced in most of the iPSC clones.
The sox family of transcription factors: versatile regulators of stem and progenitor cell fate.
- Abby Sarkar, K. Hochedlinger
- BiologyCell Stem Cell
- 3 January 2013
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