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Nuclear Receptor Gene

Nuclear Receptor Genes (NR Superfamily) encode over 300 ligand-dependent Nuclear Receptor (NRs) transcription factors: steroid, retinoid, vitamin D… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
02419922017

Related topics

Related topics

50 relations
AR protein, humanAndrogen Receptor Splice Variant 3, HumanAndrogen Receptor Splice Variant 5,6,7es, HumanBiologic Development
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Nuclear Receptor Gene
Cell Differentiation process
Homeostasis
dna binding
estrogen receptor alpha, human
Estrogen Receptors

Papers overview

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2011
2011
The Drosophila FTZ-F1 nuclear receptor mediates juvenile hormone activation of E75A gene expression through an intracellular pathway.
Juvenile hormone (JH) regulates a wide variety of biological activities in holometabolous insects, ranging from vitellogenesis… (More)
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2010
2010
Microarray analysis identifies altered regulation of nuclear receptor family members in the pre-disease state of multiple sclerosis.
Molecular mechanisms that influence susceptibility to multiple sclerosis are poorly understood. We analyzed peripheral blood gene… (More)
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2010
2010
Genome-Wide Analysis of Binding Sites and Direct Target Genes of the Orphan Nuclear Receptor NR2F1/COUP-TFI
BACKGROUND Identification of bona fide direct nuclear receptor gene targets has been challenging but essential for understanding… (More)
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2009
2009
The EWSR1/NR4A3 fusion protein of extraskeletal myxoid chondrosarcoma activates the PPARG nuclear receptor gene.
The NR4A3 nuclear receptor is implicated in the development of extraskeletal myxoid chondrosarcoma (EMC), primitive sarcoma… (More)
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2004
2004
The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation…
Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors that form a subfamily of the… (More)
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2003
2003
Acetylation and methylation in nuclear receptor gene activation.
Activation of hormone target genes requires chromatin remodeling and histone modifications. The properties of the two PRMT… (More)
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Highly Cited
2001
Highly Cited
2001
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.
Regulation of nuclear receptor gene expression involves dynamic and coordinated interactions with histone acetyl transferase (HAT… (More)
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1998
1998
Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF.
Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily. We report the cloning of a cDNA… (More)
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Highly Cited
1994
Highly Cited
1994
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.
Hepatocyte nuclear factor 4 (HNF-4) is a member of the nuclear receptor gene superfamily with unknown ligand. It has been assumed… (More)
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Highly Cited
1992
Highly Cited
1992
Evolution of the nuclear receptor gene superfamily.
Nuclear receptor genes represent a large family of genes encoding receptors for various hydrophobic ligands such as steroids… (More)
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