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Nuclear Receptor Gene

Nuclear Receptor Genes (NR Superfamily) encode over 300 ligand-dependent Nuclear Receptor (NRs) transcription factors: steroid, retinoid, vitamin D… Expand
National Institutes of Health

Related topics

Related topics

50 relations
AR protein, humanAndrogen Receptor Splice Variant 3, HumanAndrogen Receptor Splice Variant 5,6,7es, HumanBiologic Development
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Papers overview

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2016
2016
Dynamics of nuclear receptor gene expression during Pacific oyster development
BackgroundNuclear receptors are a highly conserved set of ligand binding transcription factors, with essential roles regulating… Expand
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2009
2009
The EWSR1/NR4A3 fusion protein of extraskeletal myxoid chondrosarcoma activates the PPARG nuclear receptor gene.
The NR4A3 nuclear receptor is implicated in the development of extraskeletal myxoid chondrosarcoma (EMC), primitive sarcoma… Expand
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Highly Cited
2009
Highly Cited
2009
Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates
BackgroundAbout 45% of the human genome is comprised of mobile transposable elements or "junk DNA". The exaptation or co-option… Expand
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2008
2008
Drug-regulated expression of Plasmodium falciparum P-glycoprotein homologue 1: a putative role for nuclear receptors.
Acquired resistance to therapeutic agents is a major clinical concern in the prevention/treatment of malaria. The parasite has… Expand
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Highly Cited
2004
Highly Cited
2004
The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation…
Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors that form a subfamily of the… Expand
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2003
2003
Acetylation and methylation in nuclear receptor gene activation.
Activation of hormone target genes requires chromatin remodeling and histone modifications. The properties of the two PRMT… Expand
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Review
2002
Review
2002
Peroxisome proliferator-activated receptors and the control of inflammation.
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors which form a subfamily of the… Expand
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Review
2000
Review
2000
Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis.
Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors which form a subfamily of the… Expand
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Review
1994
Review
1994
Fatty acid activation of the peroxisome proliferator activated receptor, a member of the nuclear receptor gene superfamily.
The peroxisome proliferator activated receptor is a member of the steroid receptor gene superfamily, sharing amino acid sequence… Expand
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Highly Cited
1992
Highly Cited
1992
Evolution of the nuclear receptor gene superfamily.
Nuclear receptor genes represent a large family of genes encoding receptors for various hydrophobic ligands such as steroids… Expand
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