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Androgen Receptor Splice Variant 3, Human
Known as:
Androgen Receptor Splice Variant 7
, Androgen Receptor Splice Variant 3
, AR-v7
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Androgen receptor protein that is comprised of the amino acids encoded by exons 1-3 and those encoded by cryptic exon 3 (CE3) of the human AR gene…
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National Institutes of Health
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Related topics
Related topics
21 relations
AR gene
Biologic Development
Cell Differentiation process
Cell Nucleus
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer
H. Scher
,
R. Graf
,
+13 authors
G. Heller
JAMA oncology
2018
Corpus ID: 49592745
Importance A blood test to determine whether to treat patients with metastatic castration-resistant prostate cancer (mCRPC) with…
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Highly Cited
2017
Highly Cited
2017
The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients.
M. Del Re
,
E. Biasco
,
+9 authors
R. Danesi
European urology
2017
Corpus ID: 2665702
Highly Cited
2016
Highly Cited
2016
Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer.
H. Scher
,
David S. K. Lu
,
+14 authors
R. Dittamore
JAMA oncology
2016
Corpus ID: 27024492
Importance A critical decision in the management of metastatic castration-resistant prostate cancer (mCRPC) is when to administer…
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Highly Cited
2015
Highly Cited
2015
Efficacy of Cabazitaxel in Castration-resistant Prostate Cancer Is Independent of the Presence of AR-V7 in Circulating Tumor Cells.
W. Onstenk
,
A. Sieuwerts
,
+15 authors
S. Sleijfer
European urology
2015
Corpus ID: 11092016
Highly Cited
2015
Highly Cited
2015
Androgen receptor splice variants contribute to prostate cancer aggressiveness through induction of EMT and expression of stem cell marker genes
D. Kong
,
S. Sethi
,
+4 authors
F. Sarkar
The Prostate
2015
Corpus ID: 25282333
The mechanism(s) by which androgen receptor (AR) splice variants contribute to castration‐resistant prostate cancer (CRPC) is…
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Highly Cited
2014
Highly Cited
2014
Mechanisms of the androgen receptor splicing in prostate cancer cells
L. Liu
,
N. Xie
,
S. Sun
,
S. Plymate
,
E. Mostaghel
,
X. Dong
Oncogene
2014
Corpus ID: 5317849
Prostate tumors develop resistance to androgen deprivation therapy (ADT) by multiple mechanisms, one of which is to express…
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Review
2012
Review
2012
ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.
S. Yamashita
,
K. Lai
,
+9 authors
Chawnshang Chang
Neoplasia
2012
Corpus ID: 44403109
Early studies suggested androgen receptor (AR) splice variants might contribute to the progression of prostate cancer (PCa) into…
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Highly Cited
2010
Highly Cited
2010
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
Philip A. Watson
,
Yinan Chen
,
+5 authors
C. Sawyers
Proceedings of the National Academy of Sciences
2010
Corpus ID: 25165777
Androgen receptor (AR) splice variants lacking the ligand binding domain (ARVs), originally isolated from prostate cancer cell…
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Highly Cited
2009
Highly Cited
2009
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth.
Zhiyong Guo
,
Xi Yang
,
+11 authors
Y. Qiu
Cancer research
2009
Corpus ID: 25143292
The androgen receptor (AR) plays a key role in progression to incurable androgen ablation-resistant prostate cancer (PCA). We…
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Highly Cited
2004
Highly Cited
2004
Escherichia coli Glutamate- and Arginine-Dependent Acid Resistance Systems Increase Internal pH and Reverse Transmembrane Potential
H. Richard
,
J. Foster
Journal of bacteriology
2004
Corpus ID: 11917578
ABSTRACT Due to the acidic nature of the stomach, enteric organisms must withstand extreme acid stress for colonization and…
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