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Androgen Receptor Splice Variant 5,6,7es, Human

Known as: ARv567es, Arv-12, Androgen Receptor Splice Variant 12 
Androgen receptor protein that is missing the amino acids encoded by exons 5-7 and part of the 5' end of exon 8 of the human AR gene. This variant… Expand
National Institutes of Health

Papers overview

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2018
2018
Purpose: Biomarkers aiding treatment optimization in metastatic castration-resistant prostate cancer (mCRPC) are scarce. The… Expand
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2017
2017
Prostate cancer remains dependent on androgen receptor signaling even after castration. Aberrant androgen receptor signaling in… Expand
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2017
2017
Suppression of androgen receptor (AR) activity in prostate cancer by androgen depletion or direct AR antagonist treatment… Expand
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2016
2016
PURPOSE Most prostate cancer mortality can be attributed to metastatic castration resistant prostate cancer, an advanced stage… Expand
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2015
2015
The appearance of constitutively active androgen receptor splice variants (AR-Vs) has been proposed as one of the causes of… Expand
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Highly Cited
2014
Highly Cited
2014
Upregulation of constitutively-active androgen receptor splice variants (AR-Vs) has been implicated in AR-driven tumor… Expand
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2013
2013
The development of lethal, castration resistant prostate cancer is associated with adaptive changes to the androgen receptor (AR… Expand
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2013
2013
Androgen deprivation therapy remains the primary treatment modality for patients with metastatic prostate cancer but is uniformly… Expand
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2012
2012
Advanced or metastatic prostate cancer is treated by androgen deprivation; however, patients inevitably relapse with castration… Expand
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Highly Cited
2010
Highly Cited
2010
Progression of prostate cancer following castration is associated with increased androgen receptor (AR) expression and signaling… Expand
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