Novobiocin

Known as: Streptonivicin, Novobiocin [Chemical/Ingredient], N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamide 
An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other… (More)

Topic mentions per year

Topic mentions per year

1954-2017
05010019542016

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Novobiocin, an aminocoumarin antibiotic, interferes with heat shock protein 90 and hypoxia inducible factor dependent… (More)
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Highly Cited
2011
Highly Cited
2011
MOTIVATION Datasets from high-throughput sequencing technologies have yielded a vast amount of data about organisms in… (More)
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Highly Cited
2002
Highly Cited
2002
Anatomical, electrophysiological and molecular diversity of basket cell-like interneurons in layers II-IV of rat somatosensory… (More)
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Highly Cited
2002
Highly Cited
2002
Screening of random fragments of Escherichia coli genomic DNA for their ability to increase the novobiocin resistance of a… (More)
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Highly Cited
2000
Highly Cited
2000
Heat shock protein 90 (Hsp90), one of the most abundant chaperones in eukaryotes, participates in folding and stabilization of… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Heat shock protein 90 (Hsp90) interacts with and stabilizes several oncogenic protein kinases (e.g., p185(erbB2), p60… (More)
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Highly Cited
1998
Highly Cited
1998
We report the cloning, sequence analysis, tissue distribution, functional expression, and chromosomal localization of the human… (More)
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Highly Cited
1998
Highly Cited
1998
We have recently cloned the renal electrogenic Na(+)-bicarbonate contransporter of the salamander Ambystoma tigrinum (aNBC) (M. F… (More)
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Highly Cited
1997
Highly Cited
1997
Bicarbonate transporters are the principal regulators of pH in animal cells, and play a vital role in acid-base movement in the… (More)
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Highly Cited
1976
Highly Cited
1976
Novobiocin and coumermycin are known to inhibit the replication of DNA iing of DNA catalyzed by E. coli DNA gyrase, a recently… (More)
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