W. Boron

Publications405
h-index76
Citations23,249
Highly Influential Citations1,246
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Cloning and characterization of a mammalian proton-coupled metal-ion transporter
TLDR
A new metal-ion transporter in the rat, DCT1, which has an unusually broad substrate range that includes Fe2+, Zn2+, Mn2+, Co2+, Cd2+, Cu2+, Ni2+ and Pb2+.
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Intracellular pH.
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Medical physiology : a cellular and molecular approach
Expression cloning of a mammalian proton-coupled oligopeptide transporter
TLDR
The cloning and functional characterization of a H+-coupled transporter of oligopeptides and peptide-derived antibiotics from rabbit small intestine is reported, and the PepT1 primary structure is the first reported for a proton-Coupled organic solute transporter in vertebrates.
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The SLC4 family of HCO3− transporters
TLDR
SLC4 gene products play important roles in the carriage of CO2 by erythrocytes, the absorption or secretion of H+ or HCO3− by several epithelia, as well as the regulation of cell volume and intracellular pH.
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Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors
TLDR
The intracellular pH (pHi) of squid giant axons has been measured using glass pH microelectrodes and a mathematical model explains the pHi changes caused by NH4Cl on the basis of passive movements of both NH3 and NH4+.
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The SLC4 family of HCO 3 - transporters.
TLDR
SLC4 gene products play important roles in the carriage of CO(2) by erythrocytes, the absorption or secretion of H(+) or HCO(3)(-) by several epithelia, as well as the regulation of cell volume and intracellular pH.
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Regulation of intracellular pH.
  • W. Boron
  • Biology
    Advances in physiology education
  • 1 December 2004
TLDR
Just as a temperature-control system might benefit from environmental sensors that provide clues about cold and heat loading, at least some cells seem to have extracellular CO(2) or extrace Cellular HCO(3)(-) sensors that modulate acid-base transport.
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The SLC4 family of bicarbonate (HCO₃⁻) transporters.
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pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3-.
TLDR
In the presence of CO2-HCO3-, a SITS-sensitive-H CO3- -dependent transporter is the dominant mechanism of acid extrusion and accounts for the increase in steady-state pHi on addition of HCO3 -dependent transport.
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