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No-Observed-Adverse-Effect Level

Known as: NOAEL, Level, No-Observed-Adverse-Effect, No Observed Adverse Effect Level 
The highest dosage administered that does not produce toxic effects.
National Institutes of Health

Related topics

Related topics

2 relations
Acceptable Daily Intake

Broader (1)

No-Observed-Effect Level

Papers overview

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Review
2019
Review
2019
Hormetic dose responses induced by lanthanum in plants.
Rare earth elements (REEs) have recently received particular attention due to their accumulation in the environment. Such… Expand
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Review
2018
Review
2018
Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food
Abstract The European Commission asked EFSA for a scientific opinion on the risks for animal and human health related to the… Expand
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Highly Cited
2012
Highly Cited
2012
Bisphenol A Impairs Mitochondrial Function in the Liver at Doses below the No Observed Adverse Effect Level
Bisphenol A (BPA) has been reported to possess hepatic toxicity. We investigated the hypothesis that BPA, below the no observed… Expand
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Review
2011
Review
2011
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
The 7th amendment to the EU Cosmetics Directive prohibits to put animal-tested cosmetics on the market in Europe after 2013. In… Expand
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Highly Cited
2010
Highly Cited
2010
Subchronic oral toxicity of silver nanoparticles
BackgroundThe antibacterial effect of silver nanoparticles has resulted in their extensive application in health, electronic… Expand
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Highly Cited
2003
Highly Cited
2003
Oral toxicity of the cyanobacterial toxin cylindrospermopsin in male Swiss albino mice: Determination of no observed adverse effect level for deriving a drinking water guideline value
The cyanobacterial toxin cylindrospermopsin (CYN) is a frequent contaminant of freshwaters throughout the world, including those… Expand
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Highly Cited
2001
Highly Cited
2001
Determination of an acute no-observed-adverse-effect level (NOAEL) for copper in water.
A prospective, double-blind controlled study was designed to determine the acute no-observed-adverse-effect level (NOAEL) of… Expand
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Highly Cited
2001
Highly Cited
2001
The frequency of U-shaped dose responses in the toxicological literature.
Hormesis has been defined as a dose-response relationship in which there is a stimulatory response at low doses, but an… Expand
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Review
1999
Review
1999
Nitroaromatic munition compounds: environmental effects and screening values.
Available data on the occurrence, transport, transformation, and toxicity of eight nitroaromatic munition compounds and their… Expand
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Review
1987
Review
1987
Risk assessment of the mycotoxin zearalenone.
Trans-zearalenone, a resorcylic acid lactone, also known as F-2 toxin, is a nonsteroidal estrogenic mycotoxin produced by… Expand
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