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Orthosiphon stamineus: traditional uses, phytochemistry, pharmacology, and toxicology.
A comprehensive summary of the currently available chemical, pharmacological, and toxicological investigations as well as the traditional and therapeutic uses of O. stamineus finds that it has wide traditional and pharmacological uses in various pathophysiological conditions.
Antidiabetic Properties and Mechanism of Action of Gynura procumbens Water Extract in Streptozotocin-Induced Diabetic Rats
The results showed that G. procumbens significantly decreased blood glucose levels after 14 days of treatment and improved outcome of the IPGTT, and exerted its hypoglycemic effect by promoting glucose uptake by muscles.
Antioxidant and hepatoprotective effects of Orthosiphon stamineus Benth. standardized extract.
The results of the present study indicated that the hepatoprotective effect of Orthosiphon stamineus might be ascribable to its antioxidant and free radical scavenging property.
An investigation of the anti-inflammatory and analgesic effects of Orthosiphon stamineus leaf extract.
The results of the present study support the proposal that O. stamineus has anti-inflammatory and non-narcotic analgesic activities and justify the traditional use of the plant for treating pain and inflammation.
Antioxidant Potential of Gynura procumbens
Abstract The leaves of Gynura procumbens (Merr.) Compositae, commonly called “sambung nyawa” in Malaysia, are often eaten raw with rice. The methanol extract was prepared from the dried leaves using
Safety assessment of standardised methanol extract of Cinnamomum burmannii.
MECB did not cause any mortality nor did it cause any abnormalities in the necropsy and histopathology findings of treated rats, and the LD50 for the MECB was found to be more than 2000 mg/kg.
Bioactivity-Guided Isolation of Ethyl-p-methoxycinnamate, an Anti-inflammatory Constituent, from Kaempferia galanga L. Extracts
The results validate the anti-inflammatory activity of KG which may be exerted by the inhibition of cyclooxygenases 1 and 2, and identify ethyl-p-methoxycinnamate (EPMC) as the major component, which was re-crystallized.
Potent α-glucosidase and α-amylase inhibitory activities of standardized 50% ethanolic extracts and sinensetin from Orthosiphon stamineus Benth as anti-diabetic mechanism
Alpha-glucosidase and α-amylase inhibition could the mechanisms through which the 50% ethanolic extract of O. stamineus and sinensetin exert their antidiabetic activity, indicating that it could have potential use in the management of non-insulin-dependent diabetes.
Acute and subchronic oral toxicity of Coriolus versicolor standardized water extract in Sprague-Dawley rats.
Coriolus versicolor water extract did not cause remarkable adverse effect in SD rats and in the single dose acute toxicity and repeated dose 28-day subchronic toxicity studies, there were no significant difference in body weight, relative organ weight, haematological parameters, clinical chemistry, gross pathology and histopathology between treatment and control groups.