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Nimodipine

Known as: 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate 
A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Hydrogen production through splitting of water has attracted great scientific interest because of its relevance to renewable… Expand
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Review
2008
Review
2008
In the United States stroke is the third leading cause of death and the leading cause of disability. Brain injury following… Expand
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Highly Cited
2007
Highly Cited
2007
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by the association of severe headaches with or without… Expand
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Highly Cited
2004
Highly Cited
2004
The purpose of this study was to improve the solubility and enhance the brain uptake of nimodipine (NM) in an o/w microemulsion… Expand
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Review
2001
Review
2001
The incidence of subarachnoid haemorrhage (SAH) is stable, at around six cases per 100 000 patient years. Any apparent decrease… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND AND PURPOSE The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine… Expand
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Highly Cited
1998
Highly Cited
1998
In cultures of dissociated rat hippocampal neurons, persistent potentiation and depression of glutamatergic synapses were induced… Expand
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Highly Cited
1996
Highly Cited
1996
The authors report findings from a metaanalysis of all published randomized trials of prophylactic nimodipine used in patients… Expand
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Highly Cited
1988
Highly Cited
1988
A multicenter, randomized placebo-controlled double-blind trial of nimodipine in poor-grade aneurysm patients was carried out in… Expand
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Highly Cited
1983
Highly Cited
1983
We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind… Expand
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