Nimodipine

Known as: 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate 
A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the… (More)

Topic mentions per year

Topic mentions per year

1979-2017
05010015019792017

Papers overview

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2004
2004
Eleven patients with primary thunderclap headache (TCH) were treated with oral nimodipine 30 to 60 mg every 4 hours or IV… (More)
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Highly Cited
2004
Highly Cited
2004
After chronic spinal injury, motoneurons spontaneously develop two persistent inward currents (PICs): a TTX-sensitive persistent… (More)
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2003
Highly Cited
2003
Synaptic plasticity is conspicuously dependent on the temporal order of the pre- and postsynaptic activity. Human motor cortical… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND AND PURPOSE The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine… (More)
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Highly Cited
1998
Highly Cited
1998
In cultures of dissociated rat hippocampal neurons, persistent potentiation and depression of glutamatergic synapses were induced… (More)
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Highly Cited
1995
Highly Cited
1995
The diversity of Ca2+ channel types in rat cerebellar granule neurons was investigated with whole-cell recordings (5 mM external… (More)
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Highly Cited
1992
Highly Cited
1992
1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist… (More)
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Highly Cited
1989
Highly Cited
1989
Nimodipine is one of several dihydropyridines that block calcium channels. Originally administered to improve cerebral blood flow… (More)
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Highly Cited
1984
Highly Cited
1984
Single cardiac transmembranous Ca channels have three modes of gating behaviour in the absence of drugs, expressed as current… (More)
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Highly Cited
1983
Highly Cited
1983
We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind… (More)
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