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Nimodipine

Known as: 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate 
A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (10)

AdmonBrainalCalnitKenesil

Broader (6)

Antihypertensive AgentsCalcium Channel BlockersNicotinic AcidsVasodilator Agents
Calcium Channel Antagonists [MoA]Cerebral Arterial Vasodilation [PE]Citicoline / NimodipineDihydropyridines

Papers overview

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1992
1992
X-ray analysis of changes to the atomic structure around Ni associated with the interdiffusion and mechanical alloying of pure Ni and Mo powders.
We have applied a combination of x-ray diffraction and x-ray-absorption spectroscopy to probe, in a self-consistent way, the bulk… 
Review
1988
Review
1988
Cerebrovascular and cerebral effects of nimodipine--an update.
A survey is given on the vascular and neuronal effects of calcium antagonists under physiological and pathological conditions… 
1987
1987
Safety and efficacy of nimodipine in resuscitation of patients outside hospital.
The group treated with nimodipine consisted of 22 patients with arrhythmias and the control group of matched historical controls… 
1987
1987
The effect of nimodipine on intracranial pressure. Volume-pressure studies in a primate model.
Nimodipine was administered by intravenous infusion to six male baboons before, during, and after 6 hours of middle cerebral… 
1987
1987
Dynamic and Kinetic Differences of the Vascular and Myocardial Effects of Calcium Antagonists in the Rat Heart
We studied the effects of nifedipine, nimodi-pine, verapamil, D600 (gallopamil), D888 (desmethoxy-verapamil), D890 (quaternized… 
1986
1986
Effects of nimodipine on in vitro contractility of cerebral arteries of dog, monkey, and man.
Cerebrovascular spasm in the cynomolgus monkey does not appear to be modified by nimodipine. It is possible that cerebral… 
Highly Cited
1986
Highly Cited
1986
Computerized tomography and prognosis in early aneurysm surgery.
A study of computerized tomography (CT) scans was performed in a consecutive series of 100 patients with ruptured saccular… 
1985
1985
Pharmacology of nimodipine, a calcium antagonist with preferential cerebrovascular activity
In isolated vessels in vitro nimodipine inhibits spasms induced by depolarization independently of the vessel's origin. The… 
Highly Cited
1985
Highly Cited
1985
Calcium channel antagonists inhibit the acrosome reaction and bind to plasma membranes of sea urchin sperm.
As a prerequisite to fertilization, sea urchin sperm undergo an acrosome reaction that is mediated in part by increased… 
Highly Cited
1983
Highly Cited
1983
Identification of voltage operated calcium channels by binding studies: differentiation of subclasses of calcium antagonist drugs with 3H-nimodipine radioligand binding.
3H-Nimodipine (3H-NIM) is a high affinity radioligand suitable to study Ca2+ -channels in a variety of tissues. The binding is…