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Nimodipine

Known as: 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate 
A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the… 
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (10)

AdmonBrainalCalnitKenesil

Broader (6)

Antihypertensive AgentsCalcium Channel BlockersNicotinic AcidsVasodilator Agents
Calcium Channel Antagonists [MoA]Cerebral Arterial Vasodilation [PE]Citicoline / NimodipineDihydropyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Part I: Characterization of Solid Dispersions of Nimodipine Prepared by Hot-melt Extrusion
ABSTRACT The purpose of this study was to prepare and characterize solid dispersions of nimodipine with hydroxypropyl… 
Highly Cited
2006
Highly Cited
2006
Effect of Al-SBA-15 support on catalytic functionalities of hydrotreating catalysts: I. Effect of variation of Si/Al ratio on catalytic functionalities
Highly Cited
2000
Highly Cited
2000
Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy.
Highly Cited
2000
Highly Cited
2000
A role for sodium and chloride in kainic acid-induced beading of inhibitory interneuron dendrites
Highly Cited
1993
Highly Cited
1993
Calcium homeostasis in rat septal neurons in tissue culture
Highly Cited
1990
Highly Cited
1990
Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats.
Highly Cited
1989
Highly Cited
1989
Phosphoinositide hydrolysis induced by depolarization and sodium channel activation in mouse cerebrocortical slices
Highly Cited
1987
Highly Cited
1987
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations.
Highly Cited
1986
Highly Cited
1986
Effect of nimodipine on intracellular brain pH, cortical blood flow, and EEG in experimental focal cerebral ischemia.
Intracellular brain pH, cortical blood flow, and electroencephalograms (EEG's) were recorded in severely and moderately ischemic… 
Highly Cited
1984
Highly Cited
1984
Cerebral Blood Flow and Neurologic Outcome When Nimodipine is Given after Complete Cerebral Ischemia in the Dog
Ten minutes of complete cerebral ischemia was produced in 26 dogs by temporary ligation of the aorta and the venae cavae. Twenty… 
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