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Nimodipine

Known as: 2,6-Dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate 
A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Hydrogen production through splitting of water has attracted great scientific interest because of its relevance to renewable… Expand
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Review
2008
Review
2008
In the United States stroke is the third leading cause of death and the leading cause of disability. Brain injury following… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND AND PURPOSE The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine… Expand
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Highly Cited
1998
Highly Cited
1998
  • G. Bi, M. Poo
  • The Journal of Neuroscience
  • 1998
  • Corpus ID: 16317084
In cultures of dissociated rat hippocampal neurons, persistent potentiation and depression of glutamatergic synapses were induced… Expand
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Highly Cited
1996
Highly Cited
1996
The authors report findings from a metaanalysis of all published randomized trials of prophylactic nimodipine used in patients… Expand
Review
1991
Review
1991
In patients with spinal cord injury, the primary or mechanical trauma seldom causes total transection, even though the functional… Expand
Review
1989
Review
1989
OBJECTIVE--To determine the efficacy of oral nimodipine in reducing cerebral infarction and poor outcomes (death and severe… Expand
Highly Cited
1988
Highly Cited
1988
A multicenter, randomized placebo-controlled double-blind trial of nimodipine in poor-grade aneurysm patients was carried out in… Expand
Highly Cited
1984
Highly Cited
1984
Single cardiac transmembranous Ca channels have three modes of gating behaviour in the absence of drugs, expressed as current… Expand
Highly Cited
1983
Highly Cited
1983
We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind… Expand