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Nephroblastoma

Known as: wilms tumour, nephroma, Wilms Tumor 1 
A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL… 
National Institutes of Health

Related topics

Related topics

47 relations
AGR2 wt AlleleAMER1 geneAbdominal PainAdenosarcoma
Expand

Narrower (3)

Nephroblastomatosis, fetal ascites, macrosomia and Wilms tumorWT1 wt AlleleWilms Tumor 4

Broader (1)

Sarcoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.
BACKGROUND AND AIMS microRNAs (miRNAs) are short noncoding RNAs that regulate gene expression negatively. Although a role for… 
Highly Cited
2007
Highly Cited
2007
The Genomic Landscapes of Human Breast and Colorectal Cancers
Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalog the genetic changes… 
Highly Cited
2001
Highly Cited
2001
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing
HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen… 
Review
2001
Review
2001
DNA double-strand breaks: signaling, repair and the cancer connection
To ensure the high-fidelity transmission of genetic information, cells have evolved mechanisms to monitor genome integrity. Cells… 
Review
2001
Review
2001
Genomic imprinting: parental influence on the genome
Genomic imprinting affects several dozen mammalian genes and results in the expression of those genes from only one of the two… 
Highly Cited
1998
Highly Cited
1998
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.
Highly Cited
1996
Highly Cited
1996
DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
About 90 percent of human pancreatic carcinomas show allelic loss at chromosome 18q. To identify candidate tumor suppressor genes… 
Highly Cited
1994
Highly Cited
1994
A cell cycle regulator potentially involved in genesis of many tumor types.
A putative tumor suppressor locus on the short arm of human chromosome 9 has been localized to a region of less than 40 kilobases… 
Highly Cited
1990
Highly Cited
1990
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.
Familial cancer syndromes have helped to define the role of tumor suppressor genes in the development of cancer. The dominantly… 
Highly Cited
1988
Highly Cited
1988
Genetic alterations during colorectal-tumor development.
Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed… 
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