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Nephroblastoma
Known as:
wilms tumour
, nephroma
, Wilms Tumor 1
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A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL…
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National Institutes of Health
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Related topics
Related topics
47 relations
AGR2 wt Allele
AMER1 gene
Abdominal Pain
Adenosarcoma
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Narrower (3)
Nephroblastomatosis, fetal ascites, macrosomia and Wilms tumor
WT1 wt Allele
Wilms Tumor 4
Broader (1)
Sarcoma
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.
F. Meng
,
R. Henson
,
H. Wehbe-Janek
,
K. Ghoshal
,
S. Jacob
,
T. Patel
Gastroenterology
2007
Corpus ID: 206208161
BACKGROUND AND AIMS microRNAs (miRNAs) are short noncoding RNAs that regulate gene expression negatively. Although a role for…
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Highly Cited
2007
Highly Cited
2007
The Genomic Landscapes of Human Breast and Colorectal Cancers
L. Wood
,
D. Parsons
,
+39 authors
B. Vogelstein
Science
2007
Corpus ID: 7586573
Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalog the genetic changes…
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Highly Cited
2001
Highly Cited
2001
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing
M. Ivan
,
K. Kondo
,
+7 authors
W. Kaelin
Science
2001
Corpus ID: 33725562
HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen…
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Review
2001
Review
2001
DNA double-strand breaks: signaling, repair and the cancer connection
K. Khanna
,
S. Jackson
Nature Genetics
2001
Corpus ID: 3012823
To ensure the high-fidelity transmission of genetic information, cells have evolved mechanisms to monitor genome integrity. Cells…
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Review
2001
Review
2001
Genomic imprinting: parental influence on the genome
W. Reik
,
J. Walter
Nature Reviews Genetics
2001
Corpus ID: 12050251
Genomic imprinting affects several dozen mammalian genes and results in the expression of those genes from only one of the two…
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Highly Cited
1998
Highly Cited
1998
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.
A. Yang
,
M. Kaghad
,
+6 authors
F. McKeon
Molecular cell
1998
Corpus ID: 44265210
Highly Cited
1996
Highly Cited
1996
DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
S. Hahn
,
M. Schutte
,
+8 authors
S. Kern
Science
1996
Corpus ID: 37694954
About 90 percent of human pancreatic carcinomas show allelic loss at chromosome 18q. To identify candidate tumor suppressor genes…
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Highly Cited
1994
Highly Cited
1994
A cell cycle regulator potentially involved in genesis of many tumor types.
A. Kamb
,
N. Gruis
,
+7 authors
M. Skolnick
Science
1994
Corpus ID: 28305076
A putative tumor suppressor locus on the short arm of human chromosome 9 has been localized to a region of less than 40 kilobases…
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Highly Cited
1990
Highly Cited
1990
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.
D. Malkin
,
F. Li
,
+7 authors
M. Tainsky
Science
1990
Corpus ID: 34609995
Familial cancer syndromes have helped to define the role of tumor suppressor genes in the development of cancer. The dominantly…
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Highly Cited
1988
Highly Cited
1988
Genetic alterations during colorectal-tumor development.
B. Vogelstein
,
E. Fearon
,
+7 authors
J. Bos
The New England journal of medicine
1988
Corpus ID: 34936982
Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed…
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