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Nephroblastoma

Known as: wilms tumour, nephroma, Wilms Tumor 1 
A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL… Expand
National Institutes of Health

Related topics

Related topics

47 relations
AGR2 wt AlleleAMER1 geneAbdominal PainAdenosarcoma
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Narrower (3)

Nephroblastomatosis, fetal ascites, macrosomia and Wilms tumorWT1 wt AlleleWilms Tumor 4

Broader (1)

Sarcoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The tumor suppressor protein p53 and the ferroptosis network
ABSTRACT Ferroptosis is a form of lipid peroxidation‐induced cell death that can be regulated in many ways, from altering the… Expand
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Review
2019
Review
2019
The PTEN–PI3K Axis in Cancer
The PI3K–AKT–mTOR signal transduction pathway regulates a variety of biological processes including cell growth, cell cycle… Expand
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Review
2019
Review
2019
Microfluidic modelling of the tumor microenvironment for anti-cancer drug development.
Cancer is the leading cause of death worldwide. The complex and disorganized tumor microenvironment makes it very difficult to… Expand
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Review
2019
Review
2019
Macrophage polarity in cancer: A review
Macrophages are the most abundant cells within the tumor stroma displaying noticeable plasticity, which allows them to perform… Expand
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Review
2018
Review
2018
Exosome-mediated cell-cell communication in tumor progression.
Exosomes, which are 30-150 nm lipid bilayer vehicles, have been recognized as one of the most crucial components of the tumor… Expand
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Review
2018
Review
2018
Mutant p53 as a guardian of the cancer cell
Forty years of research have established that the p53 tumor suppressor provides a major barrier to neoplastic transformation and… Expand
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Review
2018
Review
2018
The biology and role of CD44 in cancer progression: therapeutic implications
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently… Expand
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Review
2018
Review
2018
NTRK fusion-positive cancers and TRK inhibitor therapy
NTRK gene fusions involving either NTRK1, NTRK2 or NTRK3 (encoding the neurotrophin receptors TRKA, TRKB and TRKC, respectively… Expand
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Highly Cited
2001
Highly Cited
2001
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing
HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen… Expand
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Highly Cited
1988
Highly Cited
1988
Genetic alterations during colorectal-tumor development.
Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed… Expand
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