AMER1 gene

Known as: FAM123B, RP11-403E24.2, FAMILY WITH SEQUENCE SIMILARITY 123, MEMBER B 
This gene may play a role in kidney development.
National Institutes of Health

Papers overview

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2015
2015
PURPOSE Somatic mutations occur at early stages of adenoma and accumulate throughout colorectal cancer progression. The aim of… (More)
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2014
2014
β-Arrestin is a scaffold protein that regulates signal transduction by seven transmembrane-spanning receptors. Among other… (More)
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2014
2014
WTX is a tumor suppressor gene expressed during embryonic development and inactivated in 20-30% of cases of Wilms tumor, the most… (More)
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2013
2013
Osteopathia striata congenita with cranial sclerosis (OSCS) is a skeletal dysplasia caused by germline deletions of or truncating… (More)
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2011
2011
Phosphorylation of the Wnt receptor low-density lipoprotein receptor-related protein 6 (LRP6) by glycogen synthase kinase 3… (More)
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2010
2010
WTX is a novel gene mutated in a proportion of Wilms' tumors and in patients suffering from sclerosing bone dysplasia. On the… (More)
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2010
2010
WTX/AMER1 is a novel negative regulator of the WNT/beta-catenin pathway with mutations detected in Wilms' tumors and an X-linked… (More)
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Highly Cited
2009
Highly Cited
2009
Abnormalities in WNT signaling are implicated in a broad range of developmental anomalies and also in tumorigenesis. Here we… (More)
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Highly Cited
2008
Highly Cited
2008
Wilms tumor is genetically heterogeneous, and until recently only one Wilms tumor gene was known, WT1 at 11p13. However, WT1 is… (More)
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2007
2007
APC is a multifunctional tumor suppressor protein that negatively controls Wnt signaling, but also regulates cell adhesion and… (More)
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