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AMER1 gene

Known as: FAM123B, RP11-403E24.2, FAMILY WITH SEQUENCE SIMILARITY 123, MEMBER B 
This gene may play a role in kidney development.
National Institutes of Health

Papers overview

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2015
2015
Purpose: Somatic mutations occur at early stages of adenoma and accumulate throughout colorectal cancer progression. The aim of… Expand
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Highly Cited
2012
Highly Cited
2012
Somatic defects at five loci, WT1, CTNNB1, WTX, TP53 and the imprinted 11p15 region, are implicated in Wilms tumor, the commonest… Expand
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2012
2012
Osteopathia striata with cranial sclerosis (OSCS) is an X‐linked disease caused by mutations involving WTX (FAM123B), a tumor… Expand
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Highly Cited
2011
Highly Cited
2011
Phosphorylation of the Wnt receptor low‐density lipoprotein receptor‐related protein 6 (LRP6) by glycogen synthase kinase 3… Expand
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2011
2011
WTX is an X-linked tumor suppressor targeted by somatic mutations in Wilms tumor, a pediatric kidney cancer, and by germline… Expand
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Review
2011
Review
2011
Perdu B, Lakeman P, Mortier G, Koenig R, Lachmeijer AMA, Van Hul W. Two novel WTX mutations underscore the unpredictability of… Expand
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Highly Cited
2009
Highly Cited
2009
Abnormalities in WNT signaling are implicated in a broad range of developmental anomalies and also in tumorigenesis. Here we… Expand
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Highly Cited
2008
Highly Cited
2008
Wilms tumor is genetically heterogeneous, and until recently only one Wilms tumor gene was known, WT1 at 11p13. However, WT1 is… Expand
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Highly Cited
2007
Highly Cited
2007
APC is a multifunctional tumor suppressor protein that negatively controls Wnt signaling, but also regulates cell adhesion and… Expand
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2007
2007
Weak toxins are the "three-fingered" snake venoms toxins grouped together by having an additional disulfide in the N-terminal… Expand
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