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Protein FAM123B

Known as: FAM123B, WTX, Wilms Tumor Gene on the X Chromosome Protein 
Protein FAM123B (1135 aa, ~124 kDa) is encoded by the human FAM123B gene. This protein is involved in beta-catenin degradation and may play a role in… 
National Institutes of Health

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5 relations
AMER1 geneFAM123B wt AlleleNephroblastomaSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis
The X‐chromosomally linked gene WTX is a human disease gene and a member of the AMER family. Mutations in WTX are found in Wilms… 
2017
2017
Down’s Syndrome and Triple Negative Breast Cancer: A Rare Occurrence of Distinctive Clinical Relationship
Down’s syndrome (DS), the most common genetic cause of significant intellectual disability in children and adults is caused by… 
2017
2017
Clinical, Pathologic, and Genetic Features of Wilms Tumors With WTX Gene Mutation
Clinical and pathologic features of patients with WTX-mutated Wilms tumor (WT) have not been studied in detail. We characterize… 
2016
2016
Clinical, pathologic, and genetic features of Wilms tumors with WTX gene mutation.
Clinical and pathologic features of patients with WTX-mutated Wilms tumor (WT) have not been studied in detail. We characterize… 
2011
2011
Kidney cancer: An enigma remains
The tumour suppressor WTX regulates mesenchymal progenitor cell fate and lineage specification. 
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