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Negative Regulation of G1 Phase

Known as: G1 Arrest, G1 Block 
G1 Arrest consists of cellular biochemical mechanisms, responsive to diverse governing conditions (DNA damage, contact inhibition, growth factors… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis and may progress to acute myeloid leukemia (AML… 
Highly Cited
2013
Highly Cited
2013
Hepatocellular carcinoma is one of the most common and lethal cancers worldwide, especially in developing countries. In the… 
2011
2011
The largest energy consumer in the cell is the ribosome biogenesis whose aberrancy elicits various diseases in humans. It has… 
Highly Cited
2009
Highly Cited
2009
Epigenetic silencing of secreted wingless-type (Wnt) antagonists through hypermethylation is associated with tobacco smoking and… 
Highly Cited
2006
Highly Cited
2006
Deregulation of the Rb/E2F pathway in human fibroblasts results in an E2F1-mediated apoptosis dependent on Atm, Nbs1, Chk2 and… 
Highly Cited
2000
Highly Cited
2000
The ansamycin antibiotics, herbimycin A (HA) and geldanamycin (GM), bind to a conserved pocket in heat shock protein 90 (Hsp90… 
2000
2000
The p53 and p21 genes are associated with G1 arrest during the cell cycle and with apoptosis, both of which have a close… 
2000
2000
The value of p53 to predict the cytotoxic effect of two commonly used chemotherapy regimens was assessed in patients with… 
1994
1994
Staurosporine (ST), a protein kinase inhibitor, at a concentration of 20 nM arrests normal diploid fibroblasts 3 h into G1 (H. A…