Nefopam

Known as: 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, Nefopam [Chemical/Ingredient] 
Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2017
0102019722017

Papers overview

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2009
2009
BACKGROUND Induction of therapeutic hypothermia is often complicated by shivering. Nefopam reduces the shivering threshold with… (More)
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2005
2005
Opioids alone sometimes provide insufficient postoperative analgesia. Coadministration of drugs may reduce opioid use and improve… (More)
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2004
2004
In order to specify the nature of interactions between the analgesic compound nefopam and the glutamatergic system, we examined… (More)
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1999
1999
Postanaesthetic shivering affects up to 70% of patients after general anaesthesia, and may be very distressing. Various drugs… (More)
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1999
1999
Nefopam is a non-opioid analgesic agent with a central mode of action involving activation of descending pain-modulating pathways… (More)
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1999
1999
Nefopam is a clinically effective analgesic agent used to control mild to moderate pain, whose mechanism of action is unknown. We… (More)
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Highly Cited
1987
Highly Cited
1987
The formalin test in mice is a valid and reliable model of nociception and is sensitive for various classes of analgesic drugs… (More)
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1987
1987
The possible involvement of central serotonergic pathways in the mechanism of action of nefopam was investigated in male albino… (More)
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1975
1975
A new analgesic, nefopam, is chemically distinct and pharmacologically unrelated to any presently known analgesic. A comparison… (More)
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1975
1975
A respiratory study has been done to compare the respiratory effects of a potent new analgesic, nefopam, to morphine. Morphine… (More)
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