Semantic Scholar uses AI to extract papers important to this topic.
SUMMARY The discovery of novel small-molecule antibacterial drugs has been stalled for many years. The purpose of this review is… Expand Antibiotics are a major tool utilized by the health care industry to fight bacterial infections; however, bacteria are highly… Expand ABSTRACT Fluoroquinolone use in poultry production may select for resistant Escherichia coli that can be transmitted to humans… Expand BACKGROUND
Bacteria can mutate to acquire quinolone resistance by target alterations or diminished drug accumulation. Plasmid… Expand The fatty acid compositions and multiple antibiotic resistance patterns of 32 strains of Bradyrhizobium japonicum correlated with… Expand Many intercalative antitumor drugs have been shown to cleave DNA indirectly through their specific effect on the stabilization of… Expand Yeast extract (0.025%) and nalidixic acid (0.002%) were added to seawater samples and the samples were incubated for 6 h at 20… Expand A target protein for nalidixic and oxolinic acids in Escherichia coli, the nalA gene product (Pnal), was purified to homogeneity… Expand ATP-dependent DNA supercoiling catalyzed by Escherichia coli DNA gyrase was inhibited by oxolinic acid, a compound similar to but… Expand Goss, William A. (Sterling-Winthrop Research Institute, Rensselaer, N.Y.), William H. Deitz, and Thomas M. Cook. Mechanism of… Expand