Nafenopin

Known as: Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)-, Nafenopin [Chemical/Ingredient], Acid, Nafenoic 
A peroxisome proliferator that is used experimentally to promote liver tumors. It has been used as an antihyperlipoproteinemic agent.
National Institutes of Health

Papers overview

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1999
1999
Dehydroepiandrosterone (DHEA) is the only known naturally occurring compound that promotes peroxisome proliferation in rodent… (More)
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Highly Cited
1994
Highly Cited
1994
Suppression of apoptosis has been implicated as a mechanism for the hepatocarcinogenicity of the peroxisome proliferator class of… (More)
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Highly Cited
1992
Highly Cited
1992
Peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643 have been shown to activate PPAR (peroxisome… (More)
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1991
1991
We investigated the mechanism of the hepatocarcinogenic action of nafenopin (NAF), a nongenotoxic peroxisome proliferator. Groups… (More)
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1982
1982
Hepatic uptake of bilirubin and sulfobromophthalein has kinetic characteristics suggesting facilitated diffusion. Because these… (More)
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Highly Cited
1981
Highly Cited
1981
Putative preneoplastic islands were induced in rat liver by diethylnitrosamine or nitrosomorpholine administered either as single… (More)
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1977
1977
Nafenopin (2-methyl-2-[P-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy] propionic acid; Su-13,437), a potent hypolipidemic hepatic… (More)
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1977
1977
The repeated administration of the hypolipidemic agent Su-13 437 (nafenopin) to neonatal rats roughly doubled the number of… (More)
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1977
1977
The mitogenic effect of Nafenopin, a hypolipidemic hepatic peroxisome proliferator, in mouse liver has been studied in acute and… (More)
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1976
1976
The effects of long-term administration of nafenopin, a potent hypolipidemic drug with marked hepatomegalic and peroxisome… (More)
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