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NSC 338720

Known as: NSC-338720 
National Institutes of Health

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penclomedine

Papers overview

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2002
2002
Phase I clinical and pharmacokinetic study of oral penclomedine (NSC 338720) in adults with advanced solid malignancy.
Penclomedine is a synthetic alpha-picoline derivative that has shown antitumor activity both in preclinical development and in… 
1997
1997
Effect of penclomedine (NSC-338720) on telomere fusions, chromatin blebbing, and cell viability with and without telomerase activity and abrogated p53 function.
1995
1995
Biochemical pharmacology of penclomedine (NSC-338720).
1992
1992
Murine pharmacokinetics and metabolism of penclomedine [3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine, NSC 338720].
Penclomedine, a highly substituted pyridine derivative, has been selected by the National Cancer Institute for evaluation as a… 
1991
1991
Preclinical antitumor activity of penclomedine in mice: cross-resistance, schedule dependence, and oral activity against tumor xenografts in brain.
Penclomedine is 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine (NSC 338720), an alpha-picoline derivative with p.o… 
1989
1989
Preclinical antitumor activity of an alpha-picoline derivative, penclomedine (NSC 338720), on human and murine tumors.
Penclomedine, a synthetic alpha-picoline derivative, was identified as a potential antitumor agent in the P388 leukemia prescreen… 
1988
1988
Preliminary development and evaluation of a parenteral emulsion formulation of penclomedine (NSC-338720; 3,5-dichloro-2,4-dimethoxy-6-trichloromethylpyridine): a novel, practically water insoluble…
Penclomedine (NSC-338720) is a novel cytotoxic agent which has shown activity in several tumor model systems when screened as an… 
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