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NRG1 protein, human

Known as: Neuregulin 1, heregulin protein, human, acetylcholine receptor-inducing activity protein, human 
Neuregulin-1 (222 aa, ~24 kDa) is encoded by the human NRG1 gene. This protein is involved in binding to receptors from the EGF receptor family of… 
National Institutes of Health

Related topics

Related topics

24 relations
Agrin PathwayBreastCell Differentiation processCell Proliferation Regulatory Process

Broader (3)

HeregulinNeuregulin 1Neuregulins

Narrower (1)

neu Differentiation Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer.
We used whole-genome and transcriptome sequencing to identify clinically actionable genomic alterations in young adults with… 
Highly Cited
2012
Highly Cited
2012
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling
Objective Bone marrow-derived mesenchymal stem cells (BM-MSC) migrate to primary tumours and drive tumour progression. This study… 
Highly Cited
2011
Highly Cited
2011
Neuregulin 1 Promotes Excitatory Synapse Development and Function in GABAergic Interneurons
Neuregulin 1 (NRG1) and its receptor ErbB4 are both susceptibility genes of schizophrenia. However, little is known about the… 
Highly Cited
2007
Highly Cited
2007
Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population
Neuregulin 1 (NRG1) is a strong candidate for involvement in the aetiology of schizophrenia. A haplotype, initially identified as… 
Review
2003
Review
2003
Neuregulins and the neuromuscular system: 10 years of answers and questions
The neuregulins were originally discovered in searches for the acetylcholine receptor-inducing activity (ARIA), glial growth… 
Highly Cited
1997
Highly Cited
1997
Axonal Neuregulin Signals Cells of the Oligodendrocyte Lineage through Activation of HER4 and Schwann Cells through HER2 and HER3
We are interested in the signaling between axons and glia that leads to myelination and maintenance of the myelin internode, and… 
Highly Cited
1996
Highly Cited
1996
Epidermal Growth Factor-related Peptides Activate Distinct Subsets of ErbB Receptors and Differ in Their Biological Activities (*)
Numerous epidermal growth factor (EGF)-related peptide binding members of the ErbB family of receptor tyrosine kinases have been… 
Highly Cited
1994
Highly Cited
1994
Glial growth factor restricts mammalian neural crest stem cells to a glial fate
Highly Cited
1992
Highly Cited
1992
Molecular cloning of a candidate chicken prion protein.
Fractions enriched for acetylcholine receptor-inducing activity from chicken brain were found to contain a protein that was… 
Highly Cited
1988
Highly Cited
1988
Acetylcholine receptor-inducing factor from chicken brain increases the level of mRNA encoding the receptor alpha subunit.
A 42-kDa glycoprotein isolated from chicken brain, referred to as acetylcholine receptor-inducing activity (ARIA), that… 
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