Neuregulins

Known as: GGF, NRG protein, ARIA 
Neuregulin (heregulin) polypeptides have been shown to interact with and activate the ErbB2, ErbB3 and ErbB4 receptor proteins, and have been found… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Schizophrenia is a highly debilitating mental disorder that affects ∼1% of the general population, yet it continues to be poorly… (More)
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Highly Cited
2008
Highly Cited
2008
Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain elusive. We hypothesize that… (More)
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Review
2006
Review
2006
Neuregulins comprise a family of epidermal growth factor-like ligands that interact with ErbB receptor tyrosine kinases to… (More)
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Highly Cited
2006
Highly Cited
2006
Recent molecular genetics studies implicate neuregulin 1 (NRG1) and its receptor erbB in the pathophysiology of schizophrenia… (More)
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Highly Cited
2002
Highly Cited
2002
The cause of schizophrenia is unknown, but it has a significant genetic component. Pharmacologic studies, studies of gene… (More)
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Review
1997
Review
1997
yet to be identified. Like their mammalian counterparts, There has been rapid growth in our understanding of the invertebrate… (More)
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Highly Cited
1996
Highly Cited
1996
The ErbB family includes four homologous transmembrane tyrosine kinases. Whereas ErbB-1 binds to the epidermal growth factor (EGF… (More)
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Highly Cited
1995
Highly Cited
1995
VARIOUS in vitro studies have suggested that ErbB4 (HER4) is a receptor for the neuregulins, a family of closely related proteins… (More)
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Highly Cited
1995
Highly Cited
1995
THE receptor erbB2/neu is a member of the epidermal growth factor receptor (EGFR or erbB) family that also includes erbB3 and… (More)
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Highly Cited
1995
Highly Cited
1995
TWO different signalling pathways mediate the localization of acetylcholine receptors (AChRs) to synaptic sites in skeletal… (More)
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