Glial growth factor restricts mammalian neural crest stem cells to a glial fate

@article{Shah1994GlialGF,
  title={Glial growth factor restricts mammalian neural crest stem cells to a glial fate},
  author={N. Shah and M. Marchionni and I. Isaacs and P. Stroobant and D. Anderson},
  journal={Cell},
  year={1994},
  volume={77},
  pages={349-360}
}
  • N. Shah, M. Marchionni, +2 authors D. Anderson
  • Published 1994
  • Biology, Medicine
  • Cell
  • Growth factors and cytokines are thought to influence the development of uncommitted progenitor cell populations, but the issue of how these factors act on individual cells remains controversial. Such factors may act simply as selective mitogens or survival factors for cells that undergo lineage restrictions stochastically. Alternatively, they may instruct or bias multipotent cells to choose one lineage at the expense of others. Here we show that glial growth factor (GGF), previously defined as… CONTINUE READING
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