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Neuregulin 1

Known as: Neuregulin-1, Neuregulin-1 [Chemical/Ingredient], NDF Protein 
A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the… 
National Institutes of Health

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18 relations

Narrower (7)

HeregulinNRG1 protein, humanNrg1 protein, mouseheregulin beta1
In BloodNRG1 geneNRG1 wt AlleleNeuregulins

Papers overview

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2005
2005
Heregulin Induces Glial Cell Line-derived Neurotrophic Growth Factor-independent, Non-branching Growth and Differentiation of Ureteric Bud Epithelia*
We have purified a protein present in a conditioned medium derived from the metanephric mesenchyme that supports non-branching… 
2005
2005
Specific Structural Features of Heparan Sulfate Proteoglycans Potentiate Neuregulin-1 Signaling*
Neuregulins are a family of growth and differentiation factors that act through activation of cell-surface erbB receptor tyrosine… 
2003
2003
Neuregulin 1 in schizophrenia: out of Iceland
Schizophrenia is a disease that has proven difficult for scientists to crack. It is characterized by alterations in the content… 
2001
2001
Heregulin regulation of urokinase plasminogen activator and its receptor: human breast epithelial cell invasion.
Heregulin-beta1, which binds human epidermal growth factor receptors 3 and 4, promotes motility and invasiveness of breast cancer… 
Highly Cited
2000
Highly Cited
2000
Expression and regulation of c‐erbB ligands in human head and neck squamous carcinoma cells
We recently reported that multiple c‐erbB ligands differentially modulate in vitro proliferation, invasion and expression of… 
1999
1999
Coexpression of c-kit and stem cell factor in breast cancer results in enhanced sensitivity to members of the EGF family of growth factors
Kit, a tyrosine kinase growth factor receptor, and its ligand, stem cell factor (SCF), are commonly coexpressed in breast cancer… 
1998
1998
Selection of Heregulin Variants Having Higher Affinity for the ErbB3 Receptor by Monovalent Phage Display*
Heregulins (HRGs) are epidermal growth factor (egf) domain containing polypeptide growth factors that bind and activate several… 
Highly Cited
1995
Highly Cited
1995
NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells.
Neu differentiation factors (NDF) are a novel family of polypeptide factors which activate sub-class I tyrosine kinase receptors… 
1995
1995
HER4 Expression Correlates with Cytotoxicity Directed by a Heregulin-Toxin Fusion Protein (*)
We have constructed, expressed, and purified a fusion protein, HAR-TX β2, consisting of heregulin-β2 fused to a binding-defective… 
1990
1990
The effect of differing types of cloth and of contamination by non-feed nitrogen on intestinal digestion estimates using porous synthetic-fibre bags in a cow
The influence of free surface area and pore size of a synthetic-fibre bag, and flow of intestinal substances into the bag, on the… 
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