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NRAS gene

Known as: Neuroblastoma RAS Viral Oncogene Homolog Gene, NEUROBLASTOMA RAS VIRAL ONCOGENE HOMOLOG, NRAS 
This gene plays a role in signal transduction and cell cycle regulation.
National Institutes of Health

Related topics

Related topics

14 relations
Homo sapiensJuvenile Myelomonocytic LeukemiaLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeLeukemia, Myelomonocytic, Chronic

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NRAS wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Étude des mutations des gènes KRAS, NRAS, BRAF, PIK3CA, MET et de l’expression des protéines P53 et PTEN et leurs implications cliniques dans le carcinome ovarien de haut grade
Objectifs: Malgre leur grande heterogeneite histologique et moleculaire, la prise en charge clinique des carcinomes ovariens de… 
2014
2014
Abstract 2942: NRAS mutation as a predictor of response to immune-based therapies in patients with metastatic melanoma
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Background: Immune-based therapies are playing an… 
2012
2012
NRAS Mutations in Noonan Syndrome
Noonan syndrome is a genetically heterogeneous disorder caused by mutations in PTPN11, SOS1, RAF1 and less frequently in KRAS… 
Highly Cited
2007
Highly Cited
2007
Nras and Kras mutation in Japanese lung cancer patients: Genotyping analysis using LightCycler.
Activating mutations of Ras gene families have been found in a variety of human malignancies, including lung cancer, suggesting… 
2004
2004
Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes.
Highly Cited
1998
Highly Cited
1998
Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases.
1997
1997
[Gene amplification in bladder tumors].
Eight patients with transitional cell bladder carcinoma were analyzed viewing the detection of ras oncogene mutations. This… 
1996
1996
Solution structure of an oligodeoxynucleotide containing the human N-ras codon 12 sequence refined from 1H NMR using molecular dynamics restrained by nuclear Overhauser effects.
The structure of d(GGCAGGTGGTG).d(CACCACCTGCC), consisting of codons 11, 12 (underlined), and 13 of the human n-ras protooncogene… 
Review
1993
Review
1993
Clonal analysis of n-ras gene activation in acute myeloid leukemia.
Members of the ras gene family code for 21-kDa proteins (p21) located at the inner cellular membrane. Several lines of evidence… 
Review
1991
Review
1991
Genetic analysis of germ cell tumors: current progress and future prospects.
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