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Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

Known as: Leukemia, Myeloid, Chronic, Atypical, Leukemia, Philadelphia-Negative Myeloid, ACML 
A myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to… 
National Institutes of Health

Related topics

Related topics

28 relations
AnemiaBone MarrowBone marrow stem cellCCDC6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Myelodysplastic Syndromes, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.
The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid disorders with a highly variable disease course… 
Highly Cited
2010
Highly Cited
2010
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
Myeloid-derived suppressor cells (MDSCs) are a well-defined population of cells that accumulate in the tissue of tumor-bearing… 
Highly Cited
2010
Highly Cited
2010
Stable long‐term risk of leukaemia in patients with severe congenital neutropenia maintained on G‐CSF therapy
In severe congenital neutropenia (SCN), long‐term therapy with granulocyte colony‐stimulating factor (G‐CSF) has reduced… 
Review
2010
Review
2010
Copy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignancies.
Single nucleotide polymorphism arrays (SNP-A) have recently been widely applied as a powerful karyotyping tool in numerous… 
Highly Cited
2008
Highly Cited
2008
250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies.
Two types of acquired loss of heterozygosity are possible in cancer: deletions and copy-neutral uniparental disomy (UPD… 
Highly Cited
2005
Highly Cited
2005
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia.
Activating mutations in tyrosine kinases have been identified in hematopoietic and nonhematopoietic malignancies. Recently, we… 
Highly Cited
2004
Highly Cited
2004
Role of MyD88 in Diminished Tumor Necrosis Factor Alpha Production by Newborn Mononuclear Cells in Response to Lipopolysaccharide
ABSTRACT Human newborns are more susceptible than adults to infection by gram-negative bacteria. We hypothesized that this… 
Highly Cited
2003
Highly Cited
2003
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9.
Transcriptional deregulation through the production of dominant-acting chimeric transcription factors derived from chromosomal… 
Review
1999
Review
1999
Myelofibrosis with myeloid metaplasia: diagnostic definition and prognostic classification for clinical studies and treatment guidelines.
PURPOSE Myelofibrosis with myeloid metaplasia (MMM) is a chronic myeloproliferative disorder characterized by bone marrow… 
Highly Cited
1997
Highly Cited
1997
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors.
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