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NQO1*2 Allele

Known as: NAD(P)H Dehydrogenase, Quinone 1*2 Allele, NQO1*2, NQO1 C609T 
Human NQO1*2 allele is located in the vicinity of 16q22.1 and is approximately 17 kb in length. The NQO1 *2 allele has a C609T substitution in the… 
National Institutes of Health

Related topics

Related topics

8 relations
16q22.1Cytosine to Thymidine Transition AbnormalityDecreased Biochemical ActivityMetabolic Detoxication, Drug

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The relationship between NQO1 C609T and CAT C-262Tgenetic polymorphisms and the risk of age-related cataracts
Cataract is multi-factorial eye disease identified by the disturbance of the transparent ocular lens. There is significant… 
Review
2014
Review
2014
NQO1 C609T polymorphism and colorectal cancer susceptibility: a meta-analysis
Introduction A few studies have reported an association between NADP(H): quinine oxidoreductase 1 (NQO1) C609T polymorphism and… 
2013
2013
A functional NQO1 609C>T polymorphism and risk of hepatocellular carcinoma in a Chinese population
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a cytosolic flavoprotein that catalyzes the two-electron reduction of quinoid… 
2011
2011
DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma
Abstract Accumulative experimental evidence suggests feasibility of chemotherapeutic intervention targeting human cancer cells by… 
2010
2010
Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke.
2007
2007
The GST deletions and NQO1*2 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia.
2007
2007
NQO1 and NFE2L2 polymorphisms, fruit and vegetable intake and smoking and the risk of colorectal adenomas in an endoscopy‐based population
Both environment and genetics contribute to the pathogenesis and prevention of colorectal neoplasia. NAD(P)H:quinone… 
2004
2004
NAD(P)H:Quinone oxidoreductase-1 C609T polymorphism analysis in human superficial bladder cancers: relationship of genotype status to NQO1 phenotype and clinical response to Mitomycin C.
NAD(P)H:Quinone oxidoreductase-1 (NQO1) has been implicated in the bioreductive activation of the clinically active anticancer… 
Highly Cited
2003
Highly Cited
2003
NQO1 C609T polymorphism associated with esophageal cancer and gastric cardiac carcinoma in North China.
AIM To investigate the association of the NQO1 (C609T) polymorphism with susceptibility to esophageal squamous cell carcinoma… 
2001
2001
NAD(P)H: quinone oxidoreductase 1 expression in human bone marrow endothelial cells.
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