Limei Luo

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NAD(P)H:quinone oxidoreductase 1 (NQO1) is a cytosolic flavoprotein that catalyzes the two-electron reduction of quinoid compounds into hydroquinones, thus protecting cells from oxidative damage. A single base substitution (C→T) polymorphism at 609 in the NQO1 gene reduces quinone reductase activity. Thus, the lack of enzymatic activity in the homozygous(More)
P73, a p53 homolog, has some p53-like activities and plays an important role in modulating cell cycle, apoptosis, and DNA repair. A potentially functional dinucleotide polymorphism, G4C14-to-A4T14, has been identified in the 5′ untranslated region of exon 2 of the p73 gene, which may theoretically form a stem-loop structure and affect gene expression. We(More)
Caspase (CASP) 3 is an important caspase in the apoptosis pathway and plays an important role in the development and progression of cancer. We hypothesized that genetic variants in CASP 3 may modify individual susceptibility to hepatocellular carcinoma (HCC). Five hundred HCC cases in West China Hospital were selected, and 500 healthy cases with the same(More)
The parallel FDTD method based on MPI is studied on High-Performance Computer Clusters. This paper proposed several key aspects involved in the parallel computation of the FDTD. Results of a numerical example of a trihedral corner reflector, which divided the computing space to N×M×P (N,M,P≥3) sub-domains, demonstrate the validity of the(More)
The core issue of motorization development is the competition between transit and private cars. The traffic attraction is considerable in central business district, while the capacity of road network is limited. During the development of motorization, in order to guarantee inhabitant trip and prevent traffic jams, transit priority should be ensured.(More)
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