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NPR2 protein, human

Known as: EC 4.6.1.2, Atrionatriuretic Peptide Receptor, Type B, Atrial Natriuretic Peptide Receptor Type B 
Atrial natriuretic peptide receptor 2 (1047 aa, ~117 kDa) is encoded by the human NPR2 gene. This protein plays a role in peptide hormone binding and… 
National Institutes of Health

Related topics

Related topics

15 relations
Enzyme GeneGuanylate CyclaseIntegral Membrane ProteinsLigand Binding

Papers overview

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Highly Cited
2012
Highly Cited
2012
An Overgrowth Disorder Associated with Excessive Production of cGMP Due to a Gain-of-Function Mutation of the Natriuretic Peptide Receptor 2 Gene
We describe a three-generation family with tall stature, scoliosis and macrodactyly of the great toes and a heterozygous p… 
Highly Cited
2011
Highly Cited
2011
Expected declines in recruitment of walleye pollock (Theragra chalcogramma) in the eastern Bering Sea under future climate change
A statistical model is developed to link recruitment of eastern Bering Sea walleye pollock (Theragra chalcogramma) to variability… 
Highly Cited
2011
Highly Cited
2011
Estradiol promotes and maintains cumulus cell expression of natriuretic peptide receptor 2 (NPR2) and meiotic arrest in mouse oocytes in vitro.
Natriuretic peptide type C (NPPC) and its cognate receptor natriuretic peptide receptor 2 (NPR2) are essential for maintaining… 
Highly Cited
2006
Highly Cited
2006
Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B.
Natriuretic peptides (NP) mediate their effects by activating membrane-bound guanylyl cyclase-coupled receptors A (NPR-A) or B… 
Highly Cited
2006
Highly Cited
2006
Differential Proteomic Analysis of the Bacillus anthracis Secretome: Distinct Plasmid and Chromosome CO2-Dependent Cross Talk Mechanisms Modulate Extracellular Proteolytic Activities
ABSTRACT The secretomes of a virulent Bacillus anthracis strain and of avirulent strains (cured of the virulence plasmids pXO1… 
Highly Cited
1999
Highly Cited
1999
Sequence analysis of three Bacillus cereus loci carrying PIcR-regulated genes encoding degradative enzymes and enterotoxin.
PIcR is a pleiotropic regulator of extracellular virulence factors in the opportunistic human pathogen Bacillus cereus and the… 
Highly Cited
1996
Highly Cited
1996
Natriuretic peptide receptors on rat thymocytes: inhibition of proliferation by atrial natriuretic peptide.
Because the thymus expresses the natriuretic peptides (NP) as well as their respective receptors, an involvement of NP in the… 
Highly Cited
1995
Highly Cited
1995
Natriuretic Peptide Receptor-B (Guanylyl Cyclase-B) Mediates C-type Natriuretic Peptide Relaxation of Precontracted Rat Aorta (*)
The most potent known agonist for the natriuretic peptide receptor-B (NPR-B)/guanylyl cyclase-B is C-type natriuretic peptide… 
Highly Cited
1992
Highly Cited
1992
Phenotype-related alteration in expression of natriuretic peptide receptors in aortic smooth muscle cells.
To elucidate the physiological and pathophysiological roles of the natriuretic peptide family in vascular smooth muscle cells, in… 
Highly Cited
1992
Highly Cited
1992
Atrial natriuretic peptide inhibits the production and secretion of endothelin from cultured endothelial cells. Mediation through the C receptor.
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