NPM1 wt Allele

Known as: NPM1, B23, Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin) wt Allele 
Human NPM1 wild-type allele is located in the vicinity of 5q35 and is approximately 24 kb in length. This allele, which encodes nucleophosmin protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Neuroblastoma in advanced stages is one of the most intractable paediatric cancers, even with recent therapeutic advances… (More)
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Highly Cited
2008
Highly Cited
2008
The mechanisms of malignant cell transformation caused by the oncogenic, chimeric nucleophosmin (NPM)/anaplastic lymphoma kinase… (More)
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Highly Cited
2007
Highly Cited
2007
A t(2;5) chromosomal translocation resulting in expression of an oncogenic kinase fusion protein known as nucleophosmin… (More)
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Highly Cited
2006
Highly Cited
2006
Nucleophosmin (NPM/B23) is a key regulator in the regulation of a number of processes including centrosome duplication… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF… (More)
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Highly Cited
2003
Highly Cited
2003
Anaplastic Large Cell Lymphomas (ALCLs) carry translocations in which the anaplastic lymphoma kinase (ALK) gene is juxtaposed to… (More)
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Highly Cited
2002
Highly Cited
2002
The anaplastic lymphoma kinase (ALK) gene is characteristically translocated in Anaplastic Large Cell Lymphomas (ALCL) and the… (More)
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Highly Cited
1999
Highly Cited
1999
Anaplastic large cell lymphoma (ALCL) is associated with the t(2;5)(p23;q35), which generates the NPM-ALK fusion gene encoding an… (More)
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Highly Cited
1998
Highly Cited
1998
Protein B23 is an abundant nucleolar protein and a putative ribosome assembly factor which possesses an intrinsic ribonuclease… (More)
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Highly Cited
1997
Highly Cited
1997
The NPM-ALK fusion gene, formed by the t(2;5)(p23;q35) translocation in non-Hodgkin's lymphoma, encodes a 75-kDa hybrid protein… (More)
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