5q35

Mutations of SQSTM1 are an important cause of PDB, but other genes remain to be discovered. A major susceptibility locus for PDB… Expand

We isolated NSD1 from the 5q35 breakpoint in an individual with Sotos syndrome harboring a chromosomal translocation. We… Expand

Paget disease of bone (PDB) is a common disorder characterized by focal abnormalities of increased and disorganized bone turnover… Expand

Anaplastic large cell lymphomas (ALCL) are frequently associated with the t(2;5)(p23;q35). This translocation fuses the… Expand

Acute promyelocytic leukaemia (APL) exhibits a characteristic t(15;17) translocation that fuses the promyelocytic leukaemia (PML… Expand

Mutations in the gene encoding the homeobox transcription factor NKX2-5 were found to cause nonsyndromic, human congenital heart… Expand

Leukotriene C4 (LTC4) synthase catalyzes the conjugation of LTA4 with reduced GSH to form LTC4, the parent of the receptor active… Expand

The 2;5 chromosomal translocation occurs in most anaplastic large-cell non-Hodgkin9s lymphomas arising from activated T… Expand

The 2;5 chromosomal translocation occurs in most anaplastic large-cell non-Hodgkin's lymphomas arising from activated T… Expand

A chromosomal translocation involving a breakpoint on the long arm of chromosome 5 at position q35 has been reported previously… Expand