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Acute Myeloid Leukemia with Mutated NPM1

Known as: AML with Mutated NPM1, Acute Myeloid Leukemia with Cytoplasmic Nucleophosmin, NPMc+ AML 
An acute myeloid leukemia with mutation of the nucleophosmin gene. It is usually associated with normal karyotype and frequently has myelomonocytic… 
National Institutes of Health

Related topics

Related topics

15 relations
Bone MarrowBone marrow stem cellGene AbnormalityHematopoietic and Lymphoid Cell

Broader (1)

Leukemia, Myelocytic, Acute

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PF228 DIAGNOSTIC VALUE OF PU.1 LOCALIZATION IN ACUTE MYELOID LEUKEMIA WITH MUTATED NPM1
2019
2019
PS995 IMPACT OF DNMT3A MUTATIONAL STATUS IN MOLECULAR MEASURABLE RESIDUAL DISEASE CLEARANCE IN ACUTE MYELOID LEUKEMIA WITH MUTATED NPM1
Review
2019
Review
2019
The 2016 WHO classification of acute myeloid leukemia: What the practicing clinician needs to know.
  • D. Arber
  • Seminars in hematology (Print)
  • 2019
  • Corpus ID: 56675004
In 2016 a revision of the World Health Organization (WHO) classification of acute myeloid leukemia (AML) was introduced that… 
2018
2018
Pattern associated leukemia immunophenotypes and measurable disease detection in acute myeloid leukemia or myelodysplastic syndrome with mutated NPM1
The presence of measurable residual disease after therapy is a significant risk factor of relapse in patients with acute myeloid… 
Highly Cited
2013
Highly Cited
2013
Significance of FAB subclassification of "acute myeloid leukemia, NOS" in the 2008 WHO classification: analysis of 5848 newly diagnosed patients.
The World Health Organization (WHO) classifies acute myeloid leukemia (AML) via genetic, immunophenotypic, biological, and… 
Review
2010
Review
2010
New classification of acute myeloid leukemia and precursor-related neoplasms: changes and unsolved issues.
The World Health Organization (WHO) classification of lympho-hematopoietic neoplasms is increasingly based on genetic criteria… 
2010
2010
Acute myeloid leukemia with mutated nucleophosmin (NPM1): molecular, pathological, and clinical features.
The NPM1 gene encodes for nucleophosmin, a nucleolus-located shuttling protein that is involved in multiple cell functions… 
2009
2009
Acute Myeloid Leukemia with Mutated NPM1 Presenting with Life-Threatening, Either Arterial or Venous, Thromboembolism: a Report of 4 Cases.
Abstract 4135 Acute myeloid leukemia (AML) expressing mutated NPM1 gene and cytoplasmic nucleophosmin (NPMc+ AML) [Falini B et al… 
Review
2009
Review
2009
Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives
Purpose of review Nucleophosmin (NPM1) gene mutations, which cause aberrant cytoplasmic expression of nucleophosmin (NPMc+), are… 
Highly Cited
2009
Highly Cited
2009
AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features.
Acute myeloid leukemia (AML) with mutated NPM1 usually carries normal karyotype (NK), but it may harbor chromosomal aberrations… 
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