NPM1 gene

Known as: B23, NPM1, NUCLEOLAR PHOSPHOPROTEIN B23 
A fusion gene that results from a chromosomal translocation t(2;5)(p23;q35) which fuses the first 4 exons of the NPM1 gene with the last ten exons of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Many transformed lymphoma cells show immune-phenotypes resembling the corresponding normal lymphocytes; thus, they provide a… (More)
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Highly Cited
2007
Highly Cited
2007
Although STAT5A and STAT5B have some nonredundant functional properties, their distinct contributions to carcinogenesis are not… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF… (More)
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Highly Cited
2005
Highly Cited
2005
Nucleophosmin (also known as NPM, B23, NO38) is a nucleolar protein directly implicated in cancer pathogenesis, as the NPM1 gene… (More)
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Highly Cited
2002
Highly Cited
2002
Accumulating evidence indicates that expression of anaplastic lymphoma kinase (ALK), typically due to t(2;5) translocation… (More)
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Highly Cited
2002
Highly Cited
2002
Fusion tyrosine kinases (FTKs) such as BCR/ABL, TEL/ABL, TEL/JAK2, TEL/PDGF beta R, TEL/TRKC(L), and NPM/ALK arise from… (More)
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Highly Cited
2001
Highly Cited
2001
The NPM/ALK fusion gene, formed by the t(2;5) translocation in a subset of anaplastic large cell lymphomas, encodes a Mr 75,000… (More)
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Highly Cited
2000
Highly Cited
2000
More than half of anaplastic large-cell lymphomas (ALCLs) have a chromosomal translocation t(2;5) that leads to the expression of… (More)
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Highly Cited
1997
Highly Cited
1997
Retinoic acid receptors (RARs) are hormone-regulated transcription factors that control key aspects of normal differentiation… (More)
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Highly Cited
1994
Highly Cited
1994
The 2;5 chromosomal translocation occurs in most anaplastic large-cell non-Hodgkin's lymphomas arising from activated T… (More)
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