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NOTCH4 gene

Known as: MOUSE MAMMARY TUMOR VIRUS INTEGRATION SITE 3, ONCOGENE INT3, INT3 
This gene plays a regulatory role in vascular, renal and hepatic development.
National Institutes of Health

Related topics

Related topics

8 relations
Biologic DevelopmentCell Fate ControlEmbryonic DevelopmentLigand Binding

Narrower (1)

NOTCH4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Genome-wide methylation profiles in coronary artery ectasia.
Coronary artery ectasia (CAE) is a disease characterized by abnormally dilated coronary arteries. The mechanism of CAE remains… 
2016
2016
Abstract A51: Notch4 acts as an oncogenic signal in pancreatic tumorigenesis
The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between… 
2015
2015
Quercetin and INT3 Inhibits Endocrine Therapy Resistance and Epithelial to Mesenchymal Transition in MCF7 Breast Cancer Cells
2014
2014
Genetic and Pharmacologic Notch4 Inhibition Synergizes with FLT3 Tyrosine Kinase Inhibition in Vitro to More Effectively Eliminate FLT3/ITD-Positive Leukemia Cells
FMS-like tyrosine kinase-3 (FLT3) is a receptor tyrosine kinase expressed in hematopoietic stem/progenitor cells. Mutated in… 
2014
2014
A Bioinformatics-Based Bottom-up Network Reconstruction Approach to Detect Stem Cell-Related Blood Biomarkers of Cardiovascular Damage and Repair
Health Professions - Laboratory/Cellular: 3rd Place (The Ohio State University Denman Undergraduate Research Forum) 
2012
2012
Investigation of NOTCH4 coding region polymorphisms in sporadic inclusion body myositis
2012
2012
Microsatellite polymorphism in the EGFR, NOTCH4 and E2F4 genes and their association with breast cancer risk
Background The sequences of many human genes that encode proteins involved in cancer contain polymorphic microsatellites… 
2011
2011
Trp53 regulates Notch 4 signaling through Mdm2
Notch receptors and their ligands have crucial roles in development and tumorigenesis. We present evidence demonstrating the… 
Review
2011
Review
2011
Abstract 3135: Notch 1 and notch 4 biomarker expression in triple-negative invasive breast cancer
BACKGROUND: Triple-negative breast cancer (TNBC) is a high-grade tumor showing lack of expression of estrogen and progesterone… 
2005
2005
[Association study of NOTCH4 gene polymorphisms with schizophrenia and mood disorders in mixed pedigrees].
This study was to explore the relationships between NOTCH4 gene and schizophrenia (SP) and mood disorders (MD), and to search for… 
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