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NOS3 protein, human

Known as: NOS3, ECNOS protein, human, EC-NOS 
Nitric oxide synthase, endothelial (1203 aa, ~133 kDa) is encoded by the human NOS3 gene. This protein plays a role in the modulation of vascular… 
National Institutes of Health

Related topics

Related topics

17 relations
Angiogenesis PathwayAngiogenic ProcessCorticosteroid Cardioprotection PathwayEnosis

Broader (1)

Nitric Oxide Synthase Type III

Papers overview

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Review
2005
Review
2005
Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy?
Highly Cited
2005
Highly Cited
2005
Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes against Necrosis and Apoptosis
We investigated the effect of sildenafil in protection against necrosis or apoptosis in cardiomyocytes. Adult mouse ventricular… 
Highly Cited
2004
Highly Cited
2004
Carrageenan‐induced mouse paw oedema is biphasic, age‐weight dependent and displays differential nitric oxide cyclooxygenase‐2 expression
Injection of carrageenan 1% (50 μl) in the mouse paw causes a biphasic response: an early inflammatory response that lasts 6 h… 
Highly Cited
2003
Highly Cited
2003
Direct Activation of AMP-activated Protein Kinase Stimulates Nitric-oxide Synthesis in Human Aortic Endothelial Cells*
Recent studies have indicated that endothelial nitric-oxide synthase (eNOS) is regulated by reversible phosphorylation in intact… 
Highly Cited
2002
Highly Cited
2002
Basal and Stimulated Protein S-Nitrosylation in Multiple Cell Types and Tissues*
There is substantial evidence that proteinS-nitrosylation provides a significant route through which nitric oxide (NO)-derived… 
Highly Cited
1998
Highly Cited
1998
Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis.
BACKGROUND NO regulates vascular tone and structure, platelets, and monocytes. NO is synthesized by endothelial NO synthase (eNOS… 
Highly Cited
1998
Highly Cited
1998
Alterations of nitric oxide synthase expression with aging and hypertension in rats.
The activity and protein expression of endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) were investigated during… 
Highly Cited
1998
Highly Cited
1998
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats.
Two NO synthase (NOS) isoforms have been described in vessels, an endothelial constitutive NOS (eNOS) and an inducible NOS (iNOS… 
Review
1997
Review
1997
Nitric oxide synthase in models of focal ischemia.
BACKGROUND AND PURPOSE Cessation of blood flow to the brain, for even a few minutes, sets in motion a potential reversible… 
Highly Cited
1994
Highly Cited
1994
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.
Enhanced formation of nitric oxide (NO) by both the constitutive and the inducible isoforms of NO synthase (NOS) has been… 
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