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NOS2 gene

Known as: NOS2, NOS2A, NITRIC OXIDE SYNTHASE, INDUCIBLE 
This gene is involved in vasodilation and regulation of the bactericidal/tumoricidal actions of macrophages.
National Institutes of Health

Related topics

Related topics

6 relations
Intercellular Communication ProcessNOS2A protein, humanNitric Oxide SynthaseNitric Oxide Synthase Type II

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NOS2 wt Allele

Papers overview

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Highly Cited
2012
Highly Cited
2012
Anti-inflammatory effects of dichloromethane fraction from Orostachys japonicus in RAW 264.7 cells: suppression of NF-κB activation and MAPK signaling.
Highly Cited
2004
Highly Cited
2004
Interactions between NO and O2 in the microcirculation: a mathematical analysis.
Highly Cited
2003
Highly Cited
2003
Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples
AbstractKnowledge of genetic polymorphisms in gene-environment studies may contribute to more accurate identification of… 
Highly Cited
2002
Highly Cited
2002
The Protective Role of Nitric Oxide in a Neurotoxicant- Induced Demyelinating Model1
Demyelination is often associated with acute inflammatory events involving the recruitment-activation of microglia/macrophage… 
Highly Cited
2000
Highly Cited
2000
A potent inhibitor of inducible nitric oxide synthase, ONO-1714, a cyclic amidine derivative.
(1S,5S,6R,7R)-7-Chloro-3-imino-5-methyl-2-azabicyclo[4.1.0]heptane hydrochloride (ONO-1714), a novel cyclic amidine analogue… 
Highly Cited
1998
Highly Cited
1998
Dual action of iNOS-derived nitric oxide in allergen-induced airway hyperreactivity in conscious, unrestrained guinea pigs.
Using a guinea pig model of acute allergic asthma, we recently established that a deficiency of nitric oxide (NO) contributes to… 
Highly Cited
1998
Highly Cited
1998
T cell- and NK cell-independent inhibition of hepatic metastases by systemic administration of an IL-12-expressing recombinant adenovirus.
IL-12 is a potent immunoregulatory cytokine that has been shown to mediate tumor regression in a variety of tumor models. We… 
Highly Cited
1996
Highly Cited
1996
High-level expression of mouse inducible nitric oxide synthase in Escherichia coli requires coexpression with calmodulin.
We report a method to generate and purify large quantities of fully active mouse iNOS from E. coli, and show that calmodulin… 
Review
1996
Review
1996
Autotoxicity of nitric oxide in airway disease.
Though nitric oxide (NO) plays a role in many normal pulmonary functions and is involved in inflammatory and immune responses, it… 
Highly Cited
1995
Highly Cited
1995
Exogenous nitric oxide regulates IFN-gamma plus lipopolysaccharide-induced nitric oxide synthase expression in mouse macrophages.
This study was performed to determine the effects of nitric oxide (NO) on the expression of inducible NO synthase (iNOS) in mouse… 
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