FAQ

NOS2 gene

Known as: NOS2, NOS2A, NITRIC OXIDE SYNTHASE, INDUCIBLE 
This gene is involved in vasodilation and regulation of the bactericidal/tumoricidal actions of macrophages.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
010203019952017

Related topics

Related topics

6 relations
Intercellular Communication ProcessNOS2A protein, humanNitric Oxide SynthaseNitric Oxide Synthase Type II
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NOS2 wt Allele

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
NOS2 gene
Oxidation-Reduction
Nitric Oxide Synthase
Intercellular Communication Process
NOS2A protein, human
Nitric Oxide Synthase Type II

Papers overview

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Highly Cited
2011
Highly Cited
2011
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
Fibroblastic reticular cells (FRCs) and lymphatic endothelial cells (LECs) are nonhematopoietic stromal cells of lymphoid organs… (More)
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2010
2010
Glucagon-like peptide-1 increases myocardial glucose uptake via p38alpha MAP kinase-mediated, nitric oxide-dependent mechanisms in conscious dogs with dilated cardiomyopathy.
BACKGROUND We have shown that glucagon-like peptide-1 (GLP-1[7-36] amide) stimulates myocardial glucose uptake in dilated… (More)
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2007
2007
Immunomodulating activities of acidic sulphated polysaccharides obtained from the seaweed Ulva rigida C. Agardh.
Water-soluble acidic polysaccharides from the cell walls of Ulva rigida are mainly composed of disaccharides that contain… (More)
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2006
2006
Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen.
Progressive disease in the hamster model of visceral leishmaniasis, caused by Leishmania donovani, in contrast to infection in… (More)
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2006
2006
NOS2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis: contribution to the transcriptional activity
Systemic sclerosis (SSc) is a connective tissue disease characterized by tissue fibrosis. One of several complications of SSc… (More)
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Highly Cited
2003
Highly Cited
2003
Bacterial lipopolysaccharide signaling through Toll-like receptor 4 suppresses asthma-like responses via nitric oxide synthase 2 activity.
Asthma results from an intrapulmonary allergen-driven Th2 response and is characterized by intermittent airway obstruction… (More)
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2003
2003
Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren.
Several studies have focused their attention on the relationship between host genetic factors and susceptibility/resistance to… (More)
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Highly Cited
2002
Highly Cited
2002
The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and…
Hypoxia-inducible factor 1 (HIF-1), a heterodimer of HIF-1alpha and HIF-1beta subunits, is a transcriptional activator central to… (More)
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Highly Cited
2000
Highly Cited
2000
Expression of the nitric oxide synthase 2 gene is not essential for early control of Mycobacterium tuberculosis in the murine lung.
The interleukin-12 and gamma interferon (IFN-gamma) pathway of macrophage activation plays a pivotal role in controlling… (More)
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Highly Cited
1999
Highly Cited
1999
Inhibition of allergic airway inflammation in mice lacking nitric oxide synthase 2.
We have used mice rendered deficient for nitric oxide synthase 2 (NOS2) production to study the role of inducible nitric oxide… (More)
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