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NM-441

Known as: NM 441, NM441 
 
National Institutes of Health

Papers overview

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2012
2012
Since the development of norfloxacin, many fluoroquinolones with broad spectrum antibacterial activity, such as ciprofloxacin or… Expand
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Highly Cited
1998
Highly Cited
1998
NM441 is a prodrug of the new quinolone carboxylic acid antibacterial agent NM394. A rat serum enzyme (NM441-hydrolase) that… Expand
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1998
1998
AbstractObjective: To determine the potential influence of prulifloxacin (AF3012, NM441), a new antibacterial fluoroquinolone, on… Expand
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1997
1997
The pharmacokinetics of prulifloxacin ((+/-)-6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl) methyl-1-piperazinyl]-4… Expand
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1997
1997
Prulifloxacin ((+/-)-6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl) methyl-1-piperazinyl]-4-oxo-4H-[1,3]thiazeto[3,2-a… Expand
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1997
1997
The metabolism of the new quinolone antibacterial prodrug prulifloxacin ((+/-)-6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1, 3… Expand
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1994
1994
The safety and pharmacokinetics of NM441, a prodrug of a new thiazeto‐quinoline carboxylic acid derivative, NM394, were evaluated… Expand
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1993
1993
The in vitro antibacterial activity of NM394 was compared with those of other new quinolones. NM394 showed potent and broad… Expand
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1992
1992
A series of [1,3]thiazeto[3,2-a]quinoline-3-carboxylic acids and their esters were prepared and evaluated for antibacterial… Expand
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1991
1991
NM441 is a lipophilic prodrug of a new thiazeto-quinoline carboxylic acid derivative NM394, and when it is administered orally it… Expand
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