NLRP1 gene

Known as: NLR family, pyrin domain containing 1, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1, CARD7 
This gene plays a role in the induction of apoptosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
0102019972018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Toxoplasma gondii is an intracellular parasite that infects a wide range of warm-blooded species. Rats vary in their… (More)
Is this relevant?
2013
2013
Nuclear localization leucine-rich-repeat protein 1 (NLRP1) is a key regulator of the innate immune system, particularly in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Multi-protein complexes called inflammasomes have recently been identified and shown to contribute to cell death in tissue injury… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Cytopenias are key prognostic indicators of life-threatening infection, contributing to immunosuppression and mortality. Here we… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
2011
2011
NALP1 is a member of the NOD-like receptor (NLR) family of proteins that form inflammasomes. Upon cellular infection or stress… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Inflammation is a protective attempt by the host to remove injurious stimuli and initiate the tissue healing process. The… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Interleukin (IL)-1beta maturation is accomplished by caspase-1-mediated proteolysis, an essential element of innate immunity… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Several autoinflammatory disorders such as Muckle-Wells syndrome are characterized by mutations in the NALP3/cryopyrin gene… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
BACKGROUND Autoimmune and autoinflammatory diseases involve interactions between genetic risk factors and environmental triggers… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
2007
2007
Generalized vitiligo is a common, multifactorial, polygenic disease in which autoimmune loss of melanocytes results in… (More)
Is this relevant?