NLRP1 wt Allele

Known as: NLR Family, Pyrin Domain Containing 1 wt Allele, SLEV1, CARD7 
Human NLRP1 wild-type allele is located in the vicinity of 17p13.2 and is approximately 120 kb in length. This allele, which encodes NACHT, LRR and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
02420002018

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2012
2012
Regulation of hippocampal neurogenesis is poorly understood, but appears to contribute to mood and cognition. Ethanol and… (More)
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2011
2011
NALP1 is a member of the NOD-like receptor (NLR) family of proteins that form inflammasomes. Upon cellular infection or stress… (More)
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Highly Cited
2007
Highly Cited
2007
Interleukin (IL)-1beta maturation is accomplished by caspase-1-mediated proteolysis, an essential element of innate immunity… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Autoimmune and autoinflammatory diseases involve interactions between genetic risk factors and environmental triggers… (More)
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Highly Cited
2007
Highly Cited
2007
Several autoinflammatory disorders such as Muckle-Wells syndrome are characterized by mutations in the NALP3/cryopyrin gene… (More)
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Highly Cited
2007
Highly Cited
2007
Caspases are intracellular proteases that cleave substrates involved in apoptosis or inflammation. In C. elegans, a paradigm for… (More)
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2003
2003
Signaling in apoptosis and inflammation is often mediated by proteins of the death domain superfamily in the Fas/FADD/Caspase-8… (More)
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2001
2001
We report the deduced amino acid sequences of two alternately spliced isoforms, designated DEFCAP-L and -S, that differ in 44… (More)
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2001
2001
Both systemic lupus erythematosus (SLE) and vitiligo are autoimmune disorders that have strong evidence of complex genetic… (More)
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