NF2 gene

Known as: NEUROFIBROMIN 2, SCHWANNOMIN, neurofibromin 2 (merlin) 
Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Although Merlin/NF2 was discovered two decades ago as a tumor suppressor underlying Neurofibromatosis type II, its precise… (More)
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Highly Cited
2010
Highly Cited
2010
The conserved Hippo signaling pathway regulates organ size in Drosophila and mammals. While a core kinase cascade leading from… (More)
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Highly Cited
2009
Highly Cited
2009
Inactivating mutations of the neurofibromatosis 2 (NF2) gene, NF2, result predominantly in benign neurological tumors… (More)
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Highly Cited
2006
Highly Cited
2006
Merlin, the protein product of the Neurofibromatosis type-2 gene, acts as a tumour suppressor in mice and humans. Merlin is an… (More)
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Review
2005
Review
2005
The NF2 tumor-suppressor gene was cloned more than a decade ago, but the function of its encoded protein, Merlin, remains elusive… (More)
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Highly Cited
2003
Highly Cited
2003
The Nf2 tumor suppressor gene codes for merlin, a protein whose function has been elusive. We describe a novel interaction… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in the neurofibromatosis type II (NF2) tumor suppressor predispose humans and mice to tumor development. The study of… (More)
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Highly Cited
2001
Highly Cited
2001
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder whose hallmark is bilateral vestibular schwannoma. It displays a… (More)
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Highly Cited
1996
Highly Cited
1996
The gene predisposing to neurofibromatosis type 2 (NF2) on human chromosome 22 has revealed a wide variety of different mutations… (More)
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Highly Cited
1996
Highly Cited
1996
Colorectal tumors frequently have loss of heterozygosity on chromosome 22q, suggesting that inactivation of tumor suppressor gene… (More)
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