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NF2 gene

Known as: NEUROFIBROMIN 2, SCHWANNOMIN, neurofibromin 2 (merlin) 
Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Although Merlin/NF2 was discovered two decades ago as a tumor suppressor underlying Neurofibromatosis type II, its precise… Expand
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Highly Cited
2012
Highly Cited
2012
The Drosophila TEAD ortholog Scalloped is required for Yki-mediated overgrowth but is largely dispensable for normal tissue… Expand
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Highly Cited
2010
Highly Cited
2010
The conserved Hippo signaling pathway regulates organ size in Drosophila and mammals. While a core kinase cascade leading from… Expand
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Highly Cited
2006
Highly Cited
2006
Merlin, the protein product of the Neurofibromatosis type-2 gene, acts as a tumour suppressor in mice and humans. Merlin is an… Expand
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Review
2005
Review
2005
The NF2 tumor-suppressor gene was cloned more than a decade ago, but the function of its encoded protein, Merlin, remains elusive… Expand
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Highly Cited
2004
Highly Cited
2004
The genetic content of wild-type human cytomegalovirus was investigated by sequencing the 235 645 bp genome of a low passage… Expand
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Highly Cited
2001
Highly Cited
2001
Mutations in the neurofibromatosis type II (NF2) tumor suppressor predispose humans and mice to tumor development. The study of… Expand
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Highly Cited
1998
Highly Cited
1998
We have identified the human homologue of a regulatory cofactor of Na+-H+ exchanger (NHE-RF) as a novel interactor for merlin… Expand
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Highly Cited
1996
Highly Cited
1996
The gene predisposing to neurofibromatosis type 2 (NF2) on human chromosome 22 has revealed a wide variety of different mutations… Expand
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Highly Cited
1995
Highly Cited
1995
Ezrin is a membrane-cytoskeletal linking protein that is concentrated in actin-rich surface structures. It is closely related to… Expand
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