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NF2 gene

Known as: NEUROFIBROMIN 2, SCHWANNOMIN, neurofibromin 2 (merlin) 
Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.
National Institutes of Health

Related topics

Related topics

40 relations
Acoustic NeuromaAnaplastic (Malignant) Intraspinal MeningiomaAtypical meningiomaBenign Cardiac Schwannoma

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NF2 wt Allele

Papers overview

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2016
2016
Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma
2008
2008
Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin.
Highly Cited
2007
Highly Cited
2007
Genomewide suggestive linkage of opioid dependence to chromosome 14q.
The genetic predisposition to addiction to opioids and other substances is transmitted as a complex genetic trait, which… 
Highly Cited
2005
Highly Cited
2005
A genome scan of neuroticism in nicotine dependent smokers
Neuroticism is a personality factor that has consistently been demonstrated to be associated with anxiety, depression, and other… 
2003
2003
Merlin suppresses the SRE-dependent transcription by inhibiting the activation of Ras-ERK pathway.
Highly Cited
2002
Highly Cited
2002
Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene
Mutations in the Nf2 tumor suppressor gene lead to tumor formation in humans and mice and cellular overproliferation phenotypes… 
Highly Cited
2002
Highly Cited
2002
Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling.
Mutations in the neurofibromatosis 2 (NF2) gene with the resultant loss of expression of the NF2 tumor suppressor schwannomin are… 
Highly Cited
1998
Highly Cited
1998
NF2 gene in neurofibromatosis type 2 patients.
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder that predisposes to nervous system tumors. The schwannomin (also… 
Highly Cited
1994
Highly Cited
1994
Germline mutations in the neurofibromatosis type 2 tumour suppressor gene.
The recent identification of the NF2 tumour suppressor gene has enabled large scale screening for pathological mutations in the… 
Highly Cited
1990
Highly Cited
1990
Offspring protection by merlin Falco columbarius females; the importance of brood size and expected offspring survival for defense of young
SummaryNest predation was simulated by presenting a stuffed raven close to nests of merlins. This was done to examine the… 
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