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NF 449

Known as: NF-449, NF449 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Intermittent compressive force induces human mandibular‐derived osteoblast differentiation via WNT/β‐catenin signaling
Mechanical force induces an efflux of ATP that regulates osteoblast differentiation. However, the effect of mechanical force… 
2018
2018
P2X1 Receptors Amplify FcγRIIa-Induced Ca 2+ Increases and Functional Responses in Human Platelets
Abstract Platelets express key receptors of the innate immune system such as FcγRIIa and Toll-like receptors (TLR). P2X1 cation… 
2017
2017
A small-molecule screen identifies the antitrypanosomal agent suramin and analogues NF023 and NF449 as inhibitors of STAT5a/b.
2014
2014
Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and β
Zinc metalloproteinases meprin α and meprin β are implicated in a variety of diseases, such as fibrosis, inflammation and… 
2012
2012
Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity.
2008
2008
Ectodomain Lysines and Suramin Block of P2X1 Receptors
P2X1 receptors belong to a family of cation channels gated by extracellular ATP; they are found inter alia in smooth muscle… 
Highly Cited
2007
Highly Cited
2007
Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists.
2006
2006
ERK 2 activation in arteriolar and venular murine thrombosis : platelet receptor GPIb vs . P 2 X 1
The functional significance of extracellular signalregulated kinase 2 (ERK2) activation was investigated during shear induced… 
2006
2006
A novel follicle-stimulating hormone-induced G alpha h/phospholipase C-delta1 signaling pathway mediating rat sertoli cell Ca2+-influx.
FSH is known to activate Gs/cAMP signaling pathway in Sertoli cells (SCs) to support spermatogenesis. However, the molecular… 
Review
2005
Review
2005
Molecular recognition at adenine nucleotide (P2) receptors in platelets.
Transmembrane signaling through P2Y receptors for extracellular nucleotides controls a diverse array of cellular processes… 
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