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NANOG gene

Known as: Nanog homeobox, NANOG, FLJ40451 
This gene plays a role in the underlying pluripotency of inner cell mass and embryonic stem cells.
National Institutes of Health

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16 relations
Cell Differentiation processEmbryonic InductionHomo sapiensNANOG protein, human

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NANOG wt Allele

Papers overview

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Highly Cited
2014
Highly Cited
2014
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
Highly Cited
2012
Highly Cited
2012
OCT4/SOX2‐independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells
NANOG, OCT4 and SOX2 form the core network of transcription factors supporting embryonic stem (ES) cell self‐renewal. While OCT4… 
Highly Cited
2012
Highly Cited
2012
Comparative Epigenomic Annotation of Regulatory DNA
Highly Cited
2010
Highly Cited
2010
NANOG regulates glioma stem cells and is essential in vivo acting in a cross‐functional network with GLI1 and p53
A cohort of genes associated with embryonic stem (ES) cell behaviour, including NANOG, are expressed in a number of human cancers… 
Highly Cited
2010
Highly Cited
2010
Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant
Background:Ovarian cancer is the most lethal gynaecological malignancy. Although ovarian cancer patients often respond initially… 
Highly Cited
2007
Highly Cited
2007
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells.
Highly Cited
2006
Highly Cited
2006
Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features
Human embryonic stem cells (HESCs) are pluripotent cells derived from the ICM of blastocyst stage embryos. As the factors needed… 
Highly Cited
2005
Highly Cited
2005
Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma
The seminoma class of testicular germ cell tumor (TGCT) are characterized by a morphological resemblance to primordial germ cells… 
Highly Cited
2005
Highly Cited
2005
The pluripotency homeobox gene NANOG is expressed in human germ cell tumors
The NANOG gene, a member of the homeobox family of DNA binding transcription factors, was recently identified in a screen for… 
Highly Cited
2005
Highly Cited
2005
Nanog expression in mouse germ cell development.
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