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NANOG gene

Known as: Nanog homeobox, NANOG, FLJ40451 
This gene plays a role in the underlying pluripotency of inner cell mass and embryonic stem cells.
National Institutes of Health

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16 relations
Cell Differentiation processEmbryonic InductionHomo sapiensNANOG protein, human

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NANOG wt Allele

Papers overview

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2013
2013
Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294.
Highly Cited
2012
Highly Cited
2012
Prognostic Impact of the Cancer Stem Cell–Related Marker NANOG in Ovarian Serous Carcinoma
Objective The objective of this study was to evaluate the prognostic significance of NANOG expression in ovarian serous carcinoma… 
2011
2011
Brief Report: Benchmarking Human Pluripotent Stem Cell Markers During Differentiation Into the Three Germ Layers Unveils a Striking Heterogeneity: All Markers Are Not Equal
Pluripotent stem cells (PSC) are functionally characterized by their capacity to differentiate into all the cell types from the… 
Highly Cited
2009
Highly Cited
2009
Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS.
2009
2009
Statins inhibit the growth of variant human embryonic stem cells and cancer cells in vitro but not normal human embryonic stem cells
Background and purpose:  Statins inhibit proliferation of various human cancer cell lines in vitro. As human embryonic stem cells… 
Highly Cited
2009
Highly Cited
2009
Nanofibrous substrates support colony formation and maintain stemness of human embryonic stem cells
Inadequate cell numbers in culture is one of the hurdles currently delaying the application of human embryonic stem cells (hESCs… 
Highly Cited
2008
Highly Cited
2008
Conventional pluripotency markers are unspecific for bovine embryonic-derived cell-lines.
2007
2007
Towards a non-invasive method for early detection of testicular neoplasia in semen samples by identification of fetal germ cell-specific markers.
BACKGROUND Testicular germ cell tumours (TGCTs) originate from a common precursor, carcinoma in situ (CIS). Diagnosis at the CIS… 
Highly Cited
2006
Highly Cited
2006
Developmental expression of pluripotency determining factors in caprine embryos: Novel pattern of NANOG protein localization in the nucleolus
Transcription factors, POU5F1/OCT4 and NANOG, whose expression is restricted to the inner cell mass (ICM) in mouse and human… 
Highly Cited
2004
Highly Cited
2004
Transcriptional profiling of initial differentiation events in human embryonic stem cells.
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