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Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats.
Human Wharton’s Jelly Stem Cells Have Unique Transcriptome Profiles Compared to Human Embryonic Stem Cells and Other Mesenchymal Stem Cells
The ability to modulate immune responses makes hWJSCs an important compatible stem cell source for transplantation therapy in allogeneic settings without immunorejection and provides a foundation for future functional studies where the exact mechanisms of these unique properties of hW JSCs can be confirmed.
The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction--an evaluation using primates, rabbit and rat.
Teratomas from pluripotent stem cells: A clinical hurdle
This review addresses the issue of tumorigenesis and discusses approaches by which this concern may be overcome and emphasizes the need to concurrently explore alternative stem cell sources that do not confer the disadvantages of pluripotency but are widely multipotent so as to yield safe desirable tissues for clinical application as soon as possible.
Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells.
Separation of SSEA-4 and TRA-1–60 Labelled Undifferentiated Human Embryonic Stem Cells from A Heterogeneous Cell Population Using Magnetic-Activated Cell Sorting (MACS) and Fluorescence-Activated…
Both hESCs and HepG2 cells in the ‘flow-through’ fraction following MACS separation were viable in culture whereas by FACS separation only the HepG 2 cells were viable, indicating that FACS efficiently helps to eliminate the undifferentiated h ESCs based on their cell-surface antigens expressed.
Taking stem cells to the clinic: Major challenges
The hurdles all these stem cell types have to overcome before stem cell‐based therapy becomes a genuine reality are described in detail.
Human umbilical cord wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro
- K. Gauthaman, Fong Chui Yee, S. Cheyyatraivendran, A. Biswas, M. Choolani, A. Bongso
- BiologyJournal of cellular biochemistry
- 1 June 2012
Human Wharton's jelly stem cell extracts possess tumor inhibitory properties that are not specific to breast cancer cells alone and these effects are mediated via agents in its extracts.
Human umbilical cord wharton's jelly mesenchymal stem cells do not transform to tumor‐associated fibroblasts in the presence of breast and ovarian cancer cells unlike bone marrow mesenchymal stem…
- A. Subramanian, Gan Shu-Uin, Fong Chui-Yee
- Biology, MedicineJournal of cellular biochemistry
- 1 June 2012
It is confirmed that hWJSCs do not transform to the TAF phenotype and may therefore not be associated with enhanced growth of solid tumors making them a safe MSC for cell based therapies.
Human Umbilical Cord Wharton’s Jelly Stem Cells Undergo Enhanced Chondrogenic Differentiation when Grown on Nanofibrous Scaffolds and in a Sequential Two-stage Culture Medium Environment
It is concluded that hWJSCs are an attractive stem cell source for inducing chondrogenesis in vitro when grown on nanoscaffolds and exposed sequentially first to complex medium and then followed byChondrogenic medium.