N-nitroso-N-methyltyramine

Known as: 4-hydroxy-N-nitroso-N-methyl-2-phenylethylamine, NNMT, Phenol, 4-(2-(methylnitrosoamino)ethyl)- 
 
National Institutes of Health

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3 relations

Broader (2)

NitrosaminesTyramine
analogs & derivatives

Papers overview

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Highly Cited
2015
Highly Cited
2015
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition
For nearly a century developmental biologists have recognized that cells from embryos can differ in their potential to… (More)
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Highly Cited
2014
Highly Cited
2014
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes. Adipose-specific… (More)
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Highly Cited
2013
Highly Cited
2013
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
Nicotinamide N-methyltransferase (NNMT) is overexpressed in a variety of human cancers, where it contributes to tumorigenesis by… (More)
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Highly Cited
2009
Highly Cited
2009
Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia.
Polymorphisms in folate pathway genes may influence the susceptibility to acute lymphoblastic leukemia (ALL). DNA was isolated… (More)
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Highly Cited
2008
Highly Cited
2008
Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.
BACKGROUND AND AIMS Pancreatic cancer is among the most dismal of human malignancies. Current therapeutic strategies are… (More)
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Highly Cited
2008
Highly Cited
2008
Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell…
Cell migration is essential to cancer invasion and metastasis and is spatially and temporally integrated through… (More)
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Highly Cited
2005
Highly Cited
2005
Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer.
PURPOSE The goal of this study was to identify and validate novel serum markers of human colorectal cancer as potential… (More)
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Highly Cited
2005
Highly Cited
2005
Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma.
The gene expression profiles of 33 renal cell carcinomas (RCCs) and nine normal kidney samples were examined using high-density… (More)
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2005
2005
A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project.
Homocysteine (Hcy) plasma level is an independent risk marker for venous thrombosis, myocardial infarction, stroke, congestive… (More)
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2001
2001
Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population
AbstractMethylation is an important event in the biotransformation pathway for many drugs and xenobiotic compounds. We screened… (More)
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