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MutL Protein Homolog 1

Known as: Colon Cancer, Nonpolyposis Type 2 Protein, COCA2 Protein, MLH1 Protein 
Eukaryotic homolog of the bacterial MutL DNA MISMATCH REPAIR protein. It heterodimerizes with MISMATCH REPAIR ENDONUCLEASE PMS2 to form MutL alpha… Expand
National Institutes of Health

Papers overview

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2016
2016
In early reactions of DNA mismatch repair, MutS recognizes mismatched bases and activates MutL endonuclease to incise the error… Expand
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2015
2015
Fancj, the gene associated with Fanconi anemia (FA) Complementation Group J, encodes a DNA helicase involved in homologous… Expand
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2013
2013
Mismatch repair (MMR) safeguards against genomic instability and is required for efficient Ig class switch recombination (CSR… Expand
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2013
2013
We report on a case of synchronous endometrial and ovarian cancer in a patient with Lynch syndrome. An endometrial biopsy… Expand
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2011
2011
Intensive use of antimicrobial agents in health care settings not only leads to the selection of multiresistant nosocomial… Expand
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2009
2009
The methyl-directed mismatch repair (MMR) mechanism has been extensively studied in vitro and in vivo, but one of the… Expand
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2006
2006
The DNA binding properties of the mismatch repair protein MutL and their importance in the repair process have been controversial… Expand
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2003
2003
The mismatch repair (MMR) protein Msh2 has been shown to function in the apoptotic response to alkylating agents in vivo. Here… Expand
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2003
2003
A simple genetic system has been developed to test the effect of over-expression of wild-type or mutated human MutL homologue 1… Expand
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Highly Cited
1996
Highly Cited
1996
The amiB-mutL-miaA-hfq-hflX-hflK-hflC superoperon of Escherichia coli contains genes that are important for diverse cellular… Expand
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