Skip to search formSkip to main contentSkip to account menu

MutL Protein Homolog 1

Known as: Colon Cancer, Nonpolyposis Type 2 Protein, COCA2 Protein, MLH1 Protein 
Eukaryotic homolog of the bacterial MutL DNA MISMATCH REPAIR protein. It heterodimerizes with MISMATCH REPAIR ENDONUCLEASE PMS2 to form MutL alpha… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
In early reactions of DNA mismatch repair, MutS recognizes mismatched bases and activates MutL endonuclease to incise the error… 
2015
2015
Fancj, the gene associated with Fanconi anemia (FA) Complementation Group J, encodes a DNA helicase involved in homologous… 
2013
2013
Mismatch repair (MMR) safeguards against genomic instability and is required for efficient Ig class switch recombination (CSR… 
2011
2011
ABSTRACT Intensive use of antimicrobial agents in health care settings not only leads to the selection of multiresistant… 
2011
2011
Colorectal cancer is the third most common cancer in women and fourth in men, with respect to incidence, and 529,000 deaths… 
2009
2009
The methyl-directed mismatch repair (MMR) mechanism has been extensively studied in vitro and in vivo, but one of the… 
2006
2006
The DNA binding properties of the mismatch repair protein MutL and their importance in the repair process have been controversial… 
2003
2003
A simple genetic system has been developed to test the effect of over-expression of wild-type or mutated human MutL homologue 1… 
Highly Cited
1996
Highly Cited
1996
The amiB-mutL-miaA-hfq-hflX-hflK-hflC superoperon of Escherichia coli contains genes that are important for diverse cellular…