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MLH1 gene

Known as: MutL Homolog 1 Gene, HNPCC, HNPCC2 
This gene plays a role in DNA mismatch repair.
National Institutes of Health

Related topics

Related topics

11 relations
DNA RepairHereditary Non-Polyposis Colon Cancer Type 2MLH1 Gene MutationMLH1 gene methylation:Arb:Pt:Tiss:Ord:Molgen

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MLH1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Immune Response Against Frameshift- Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers
ating customized screening guidelines based on gender, race, and lifestyle factors (such as smoking). Although we acknowledged… 
2008
2008
Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers. Authors' reply
2008
2008
Modifier Genes and HNPCC: Variable phenotypic expression in HNPCC and the search for modifier genes
Modifier Genes and HNPCC: Variable phenotypic expression in HNPCC and the search for modifier genes 
2004
2004
Chemotherapy resistant ovarian cancer in carriers of an hMSH2 mutation?
Hereditary Non-Polyposis Colorectal Cancer (HNPCC, Lynch syndrome) is an autosomal dominant condition of cancer susceptibility… 
2003
2003
Experience of discharge from colonoscopy of mutation negative HNPCC family members
Hereditary non-polyposis colorectal cancer (HNPCC or Lynch syndrome) is an autosomal dominant predisposition for early onset… 
2002
2002
An MLH1 haplotype is over-represented on chromosomes carrying an HNPCC predisposing mutation in MLH1
Background: The mismatch repair gene, MLH1, appears to occur as two main haplotypes at least in white populations. These are… 
2000
2000
Allelic loss in human intrahepatic cholangiocarcinoma: Correlation between chromosome 8p22 and tumor progression
Intrahepatic cholangiocarcinoma (ICC) is the second most common malignant primary tumor of the liver in Japan. Despite progress… 
1999
1999
Two types of sporadic multiple colorectal cancers with and without HNPCC-like genetic instability.
BACKGROUND/AIMS Sporadic multiple colorectal cancers (MCCs) potentially have similar genetic alterations to hereditary… 
1996
1996
Detection of Tn, sialosyl-Tn and T antigens in hereditary nonpolyposis colorectal cancer
The simple mucin-type carbohydrate antigens Tn, sialosyl-Tn, T and the ‘cryptic’ sialylated variant of the last represent the… 
1988
1988
Demonstration of altered cellular DNA content distribution in long-term colon epithelial cell lines with colon cancer genotypes.
During prolonged culture (7-40 passages assayed) DNA distribution was constant in IVT-negative lines with FPC genotype and in IVT… 
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