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MLH1 gene methylation:Arb:Pt:Tiss:Ord:Molgen

Known as: MLH1 ?????:???:???:?????:???:???????????, MLH1 genmethylatie:Arbitrair:Moment:Weefsel en uitstrijkjes:Ordinaal:Molgen, MLH1 ??? ?????????????:??????:??????:??:???:?????? 
 
National Institutes of Health

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Body tissueGenesMLH1 geneMolecular Pathology Tests
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Papers overview

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2015
2015
Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer.
BACKGROUND Colorectal cancers (CRCs) that have microsatellite instability (MSI) and mutL homolog 1 (MLH1) immunoloss are observed… Expand
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2013
2013
Mother-to-offspring Inheritance of MLH1 Promotor Hypermethylation
 
Is this relevant?
2013
2013
Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers.
Two colorectal cancer (CRC) susceptibility loci have been found to be significantly associated with an increased risk of CRC in… Expand
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Highly Cited
2008
Highly Cited
2008
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.
Genetic variations in DNA repair may impact repair functions, DNA damage and breast cancer risk. Using data/samples collected… Expand
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Highly Cited
2006
Highly Cited
2006
Uneven chromosome contraction and expansion in the maize genome.
Maize (Zea mays or corn), both a major food source and an important cytogenetic model, evolved from a tetraploid that arose about… Expand
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2006
2006
Endometrial cancer risk is associated with variants of the mismatch repair genes MLH1 and MSH2.
Women with germ-line mutations in the mismatch repair genes (responsible for hereditary nonpolyposis colorectal cancer) face an… Expand
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2005
2005
Low Allele Frequency of MLH1 D132H in American Colorectal and Endometrial Cancer Patients
PURPOSEHereditary nonpolyposis colon cancer is caused by mutations in DNA mismatch repair genes, predominantly MLH1 and MSH2… Expand
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Highly Cited
2005
Highly Cited
2005
Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining.
Microsatellite analysis (MSA) in tumour tissue is useful for pre-selection of hereditary non-polyposis colorectal cancer (HNPCC… Expand
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Highly Cited
2001
Highly Cited
2001
MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families.
PURPOSE Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by the clustering of… Expand
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1997
1997
Crohn's disease and ulcerative colitis are associated with the DNA repair gene MLH1.
OBJECTIVE The purpose of this study was to determine whether there is an association between Crohn's disease and ulcerative… Expand
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