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MLH1 protein, human

Known as: MGC5172, Mismatch Repair Protein MLH1, hMLH1 protein, human 
DNA mismatch repair protein Mlh1 (756 aa, ~85 kDa) is encoded by the human MLH1 gene. This protein is involved in post-replicative DNA mismatch… 
National Institutes of Health

Related topics

Related topics

25 relations
Adenosine TriphosphatasesBreastCell NucleusColon structure (body structure)

Broader (1)

MutL Protein Homolog 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Hypomethylation of mismatch repair genes MLH1 and MSH2 is associated with chemotolerance of breast carcinoma: Clinical significance
The aim of the study was to understand the importance of mismatch repair genes MLH1 and MSH2 in chemotolerance and prognosis of… 
2018
2018
The MLH1 ATPase domain is needed for suppressing aberrant formation of interstitial telomeric sequences.
Review
2018
Review
2018
Incompatibilities in Mismatch Repair Genes MLH1-PMS1 Contribute to a Wide Range of Mutation Rates in Human Isolates of Baker’s Yeast
Baker’s yeast bearing incompatible MLH1 and PMS1 mismatch repair alleles are mutators that can adapt more rapidly to stress—but… 
2013
2013
The combined effects of temperature and CO2 lead to altered gene expression in Acropora aspera
This study explored the interactive effects of near-term CO2 increases (40–90 ppm above current ambient) during a simulated… 
2010
2010
天津地区人群 hMLH1 和 hMSH2 基因多态性与散发性结直肠癌易感性的关系
2007
2007
MLH1-Keimbahnmethylierung als Ursache für das hereditäre nicht-Polyposis-assoziierte kolorektale Karzinom Syndrom (HNPCC)
The present model of colorectal carcinogenesis includes the step-wise progression from adenoma to invasive cancer. It is now… 
2006
2006
In vitro analysis of genomic instability triggered by BRCA1 missense mutations
The BRCA1 tumor suppressor gene encodes a phosphoprotein involved in many cellular key functions including DNA repair… 
2006
2006
First report of a de novo germline mutation in the MLH1 gene.
Hereditary non-polyposis colorectal carcinoma (HNPCC) is an autosomal dominant disorder associated with colorectal and… 
1998
1998
MOLEKULARE DIAGNOSTIK BEIM HEREDITAREN UND SPORADISCHEN COLORECTALEN CARCINOM : ERSTE EIGENE ERGEBNISSE
Wir fuhren seit August 1996 in Kooperation bei colorectalen Carcinomen molekulare Diagnostik durch. Bisher sind 26 von 51… 
1996
1996
Detection of Tn, sialosyl-Tn and T antigens in hereditary nonpolyposis colorectal cancer
The simple mucin-type carbohydrate antigens Tn, sialosyl-Tn, T and the ‘cryptic’ sialylated variant of the last represent the… 
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