MLH1 protein, human

Known as: MGC5172, Mismatch Repair Protein MLH1, hMLH1 protein, human 
DNA mismatch repair protein Mlh1 (756 aa, ~85 kDa) is encoded by the human MLH1 gene. This protein is involved in post-replicative DNA mismatch… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
02419942018

Papers overview

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2015
2015
We examined the influence of MLH1 c.-93G>A, MSH2 c.211 + 9C>G, MSH3 c.3133G>A and EXO1 c.1765G>A polymorphisms, involved in DNA… (More)
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2013
2013
This study explored the interactive effects of near-term CO2 increases (40–90 ppm above current ambient) during a simulated… (More)
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2009
2009
PURPOSE MLH1 is a key DNA mismatch repair (MMR) protein involved in maintaining genomic stability by participating in the repair… (More)
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2006
2006
The DNA binding properties of the mismatch repair protein MutL and their importance in the repair process have been controversial… (More)
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2004
2004
PURPOSE To investigate the link between microsatellite instability and epigenetic silencing of the MLH1 gene in the human… (More)
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2004
2004
Background: Exonic deletions in MSH2 and MLH1 are significant contributors to the mutation spectrum in HNPCC, and heterozygous… (More)
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2004
2004
Women predisposed to hereditary nonpolyposis colorectal cancer are at high risk of developing endometrial carcinoma at a young… (More)
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2003
2003
Defects in DNA mismatch repair (MMR) are common in human cancers, confer tolerance to certain types of chemotherapeutic agents… (More)
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2003
2003
BACKGROUND & AIMS Hereditary nonpolyposis colorectal cancer is associated with mismatch repair deficiency. Most predisposing… (More)
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2000
2000
Mismatch repair (MMR) deficiency, which underlies hereditary nonpolyposis colorectal cancer, has recently been linked to a number… (More)
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