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MLH1 protein, human

Known as: MGC5172, Mismatch Repair Protein MLH1, hMLH1 protein, human 
DNA mismatch repair protein Mlh1 (756 aa, ~85 kDa) is encoded by the human MLH1 gene. This protein is involved in post-replicative DNA mismatch… Expand
National Institutes of Health

Papers overview

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2018
2018
MLH1 and PMS2 proteins form the MutLα heterodimer, which plays a major role in DNA mismatch repair (MMR) in humans. Mutations in… Expand
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2018
2018
Genome instability gives rise to cancer. MLH1, commonly known for its important role in mismatch repair (MMR), DNA damage… Expand
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2015
2015
The preparation of 7-Fc(+) -8-Fc-7,8-nido-[C2 B9 H10 ](-) (Fc(+) FcC2 B9 (-) ) demonstrates the successful incorporation of a… Expand
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2013
2013
This study explored the interactive effects of near-term CO2 increases (40–90 ppm above current ambient) during a simulated… Expand
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2013
2013
Poly(ADP-ribose) polymerase inhibitors (PARPi) are currently evaluated in clinical trials in combination with topoisomerase I… Expand
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2013
2013
The human DNA mismatch repair (MMR) gene family comprises four MutL paralogues capable of forming heterodimeric MutLα (MLH1-PMS2… Expand
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2010
2010
The involvement of MLH1 in several mismatch repair-independent cellular processes has been reported. In an attempt to gain… Expand
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2006
2006
Hereditary non-polyposis colorectal carcinoma (HNPCC) is an autosomal dominant disorder associated with colorectal and… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: Genetic polymorphisms of DNA repair genes seem to determine the DNA repair capacity, which in turn may affect the risk… Expand
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2003
2003
BACKGROUND & AIMS Hereditary nonpolyposis colorectal cancer is associated with mismatch repair deficiency. Most predisposing… Expand
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