Monocyte Chemoattractant Protein 4

Known as: MCP-4, Small Inducible Cytokine A13, C-C Motif Chemokine 13 
C-C motif chemokine 13 (98 aa, ~11 kDa) is encoded by the human CCL13 gene. This protein is involved in leukocyte chemotaxis and inflammation.
National Institutes of Health

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Biologic DevelopmentCCL13 geneCCL13 wt AlleleCentral Nervous System
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Monocyte Chemoattractant Proteins

Papers overview

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2008
2008
Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13).
Monocyte chemoattractant proteins (MCPs) belong to the CC chemokine family and are involved in many (patho)physiological… (More)
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2006
2006
Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects.
OBJECTIVE Chronic inflammation observed in obesity has been reported to be implicated in the development of atherosclerosis. We… (More)
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Highly Cited
2004
Highly Cited
2004
A bridging domain method for coupling continua with molecular dynamics
A bridging domain method for coupling continuum models with molecular models is described. In this method, the continuum and… (More)
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Highly Cited
2003
Highly Cited
2003
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.
Bacterially expressed heterotrimeric (alpha1, beta1, and gamma1) wild-type, catalytically inactive, and constitutively active… (More)
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2000
2000
Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis.
BACKGROUND Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with tissue eosinophilia and the activation… (More)
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Highly Cited
1999
Highly Cited
1999
The Caenorhabditis elegans gene ncc-1 encodes a cdc2-related kinase required for M phase in meiotic and mitotic cell divisions, but not for S phase.
We have identified six protein kinases that belong to the family of cdc2-related kinases in Caenorhabditis elegans. Results from… (More)
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Highly Cited
1998
Highly Cited
1998
Ontogeny of cation-Cl- cotransporter expression in rat neocortex.
Neuronal precursors and immature cortical neurons actively accumulate Cl- and as a consequence depolarize in response to GABAA… (More)
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Highly Cited
1997
Highly Cited
1997
High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.
Eosinophil leukocytes express high numbers of the chemokine receptor CCR3 which binds eotaxin, monocyte chemotactic protein (MCP… (More)
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Highly Cited
1996
Highly Cited
1996
Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through…
The chemokines are a large family of cytokines that regulate the complex and precise recruitment of immune cells into… (More)
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Highly Cited
1996
Highly Cited
1996
Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin
A novel human CC chemokine complementary DNA was identified in a library constructed from human fetal RNA, cloned into a… (More)
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