Atomic force microscopy
The atomic force microscope can resolve individual atoms and molecules on some sample surfaces — even nonconducting samples in water or other fluids.
A nondestructive method for determining the spring constant of cantilevers for scanning force microscopy
The spring constant of microfabricated cantilevers used in scanning force microscopy (SFM) can be determined by measuring their resonant frequencies before and after adding small end masses. These…
Measuring the viscoelastic properties of human platelets with the atomic force microscope.
Molecular mechanistic origin of the toughness of natural adhesives, fibres and composites
Natural materials are renowned for their strength and toughness,,,,. Spider dragline silk has a breakage energy per unit weight two orders of magnitude greater than high tensile steel,, and is…
Microindentation for In Vivo Measurement of Bone Tissue Mechanical Properties in Humans
It is concluded that BMT, by inducing microscopic fractures, directly measures bone mechanical properties at the tissue level and may provide clinicians and researchers with a direct in vivo measurement of bone tissue resistance to fracture.
Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture
Evidence is found that bone consists of mineralized collagen fibrils and a non-fibrillar organic matrix, which acts as a ‘glue’ that holds the mineralized fibril together, and it is believed that this glue may resist the separation of mineralization of bone composite.
Molecular Cloning and Characterization of Lustrin A, a Matrix Protein from Shell and Pearl Nacre of Haliotis rufescens *
- Xue-qin Shen, A. Belcher, P. Hansma, G. Stucky, D. Morse
- BiologyJournal of Biological Chemistry
- 19 December 1997
The cDNA coding for Lustrin A, a newly described matrix protein from the nacreous layer of the shell and pearl produced by the abalone, Haliotis rufescens, a marine gastropod mollusc, is cloned and characterized.
The scanning ion-conductance microscope.
A scanning ion-conductance microscope (SICM) has been developed that can image the topography of nonconducting surfaces that are covered with electrolytes and sample and image the local ion currents above the surfaces.
Bone indentation recovery time correlates with bond reforming time
- James B. Thompson, J. Kindt, B. Drake, H. Hansma, D. Morse, P. Hansma
- Materials ScienceNature
- 13 December 2001
It is suggested that the sacrificial bonds found within or between collagen molecules may be partially responsible for the toughness of bone, which contains polymers with ‘sacrificial bonds’ that both protect the polymer backbone and dissipate energy.
Control of crystal phase switching and orientation by soluble mollusc-shell proteins
IN the initial stages of the biomineralization of abalone shells, a primer layer of oriented calcite crystals grows on a nucleating protein sheet1,2. The deposition of this primer is followed by an…